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Comparison of the effect of calcium gluconate and batroxobin on the release of transforming growth factor beta 1 in canine platelet concentrates

Overview of attention for article published in BMC Veterinary Research, July 2012
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Title
Comparison of the effect of calcium gluconate and batroxobin on the release of transforming growth factor beta 1 in canine platelet concentrates
Published in
BMC Veterinary Research, July 2012
DOI 10.1186/1746-6148-8-121
Pubmed ID
Authors

Raul F Silva, Raul F Silva, Jorge U Carmona, Cleuza MF Rezende

Abstract

The clinical use of autologous platelet concentrates (also known as platelet-rich plasma) on the field of regenerative therapy, in the last decade has been the subject of several studies especially in equine medicine and surgery. The objectives of this study was: 1) to describe and compare the cellular population in whole blood, lower fraction (A) and upper fraction (B) of platelet concentrates, 2) to measure and compare the transforming growth factor beta 1 (TGF-β1) concentration in plasma and both platelet concentrates after be activated with calcium gluconate or batroxobin plus calcium gluconate and, 3) to determine correlations between cell counts in platelet concentrates and concentrations of TGF-β1. Blood samples were taken from 16 dogs for complete blood count, plasma collection and platelet concentrates preparation. The platelet concentrates (PC) were arbitrarily divided into two fractions, specifically, PC-A (lower fraction) and PC-B (upper fraction). The Platelet concentrates were analyzed by hemogram. After activated with calcium gluconate or batroxobin plus calcium gluconate, TGF-β1 concentration was determined in supernatants of platelet concentrates and plasma.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 4%
Peru 1 4%
Canada 1 4%
Brazil 1 4%
Unknown 20 83%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 29%
Student > Postgraduate 4 17%
Student > Ph. D. Student 4 17%
Other 3 13%
Student > Master 3 13%
Other 3 13%
Readers by discipline Count As %
Medicine and Dentistry 11 46%
Agricultural and Biological Sciences 4 17%
Veterinary Science and Veterinary Medicine 3 13%
Materials Science 2 8%
Neuroscience 1 4%
Other 2 8%
Unknown 1 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2012.
All research outputs
#2,902,296
of 3,628,714 outputs
Outputs from BMC Veterinary Research
#498
of 609 outputs
Outputs of similar age
#55,350
of 74,842 outputs
Outputs of similar age from BMC Veterinary Research
#24
of 36 outputs
Altmetric has tracked 3,628,714 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 609 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.