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Single-protein nanomechanical mass spectrometry in real time

Overview of attention for article published in Nature Nanotechnology, August 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
8 news outlets
blogs
5 blogs
twitter
18 X users
patent
19 patents
facebook
11 Facebook pages
wikipedia
1 Wikipedia page
reddit
1 Redditor

Citations

dimensions_citation
447 Dimensions

Readers on

mendeley
370 Mendeley
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Title
Single-protein nanomechanical mass spectrometry in real time
Published in
Nature Nanotechnology, August 2012
DOI 10.1038/nnano.2012.119
Pubmed ID
Authors

M. S. Hanay, S. Kelber, A. K. Naik, D. Chi, S. Hentz, E. C. Bullard, E. Colinet, L. Duraffourg, M. L. Roukes

Abstract

Nanoelectromechanical systems (NEMS) resonators can detect mass with exceptional sensitivity. Previously, mass spectra from several hundred adsorption events were assembled in NEMS-based mass spectrometry using statistical analysis. Here, we report the first realization of single-molecule NEMS-based mass spectrometry in real time. As each molecule in the sample adsorbs on the resonator, its mass and position of adsorption are determined by continuously tracking two driven vibrational modes of the device. We demonstrate the potential of multimode NEMS-based mass spectrometry by analysing IgM antibody complexes in real time. NEMS-based mass spectrometry is a unique and promising new form of mass spectrometry: it can resolve neutral species, provide a resolving power that increases markedly for very large masses, and allow the acquisition of spectra, molecule-by-molecule, in real time.

X Demographics

X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 370 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 8 2%
France 3 <1%
Canada 3 <1%
Japan 2 <1%
Italy 1 <1%
Brazil 1 <1%
Germany 1 <1%
United Kingdom 1 <1%
Peru 1 <1%
Other 5 1%
Unknown 344 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 123 33%
Researcher 76 21%
Student > Master 39 11%
Student > Doctoral Student 15 4%
Student > Bachelor 14 4%
Other 40 11%
Unknown 63 17%
Readers by discipline Count As %
Engineering 98 26%
Physics and Astronomy 87 24%
Chemistry 39 11%
Agricultural and Biological Sciences 37 10%
Materials Science 17 5%
Other 27 7%
Unknown 65 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 137. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2023.
All research outputs
#304,417
of 25,460,914 outputs
Outputs from Nature Nanotechnology
#247
of 3,750 outputs
Outputs of similar age
#1,441
of 187,043 outputs
Outputs of similar age from Nature Nanotechnology
#3
of 43 outputs
Altmetric has tracked 25,460,914 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,750 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,043 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.