Title |
Influence of HTLV-1 on the clinical, microbiologic and immunologic presentation of tuberculosis
|
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Published in |
BMC Infectious Diseases, August 2012
|
DOI | 10.1186/1471-2334-12-199 |
Pubmed ID | |
Authors |
Maria de Lourdes Bastos, Silvane B Santos, Anselmo Souza, Brooke Finkmoore, Ohana Bispo, Tasso Barreto, Ingrid Cardoso, Iana Bispo, Flávia Bastos, Daniele Pereira, Lee Riley, Edgar M Carvalho |
Abstract |
HTLV-1 is associated with increased susceptibility to Mycobacterium tuberculosis infection and severity of tuberculosis. Although previous studies have shown that HTLV-1 infected individuals have a low frequency of positive tuberculin skin test (TST) and decreasing in lymphoproliferative responses compared to HTLV-1 uninfected persons, these studies were not performed in individuals with history of tuberculosis or evidence of M. tuberculosis infection. Therefore the reasons why HTLV-1 infection increases susceptibility to infection and severity of tuberculosis are not understood.The aim of this study was to evaluate how HTLV-1 may influence the clinical, bacteriologic and immunologic presentation of tuberculosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 67 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 14 | 20% |
Researcher | 13 | 19% |
Student > Master | 8 | 12% |
Student > Doctoral Student | 5 | 7% |
Student > Ph. D. Student | 5 | 7% |
Other | 12 | 17% |
Unknown | 12 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 35% |
Agricultural and Biological Sciences | 11 | 16% |
Immunology and Microbiology | 6 | 9% |
Nursing and Health Professions | 6 | 9% |
Environmental Science | 1 | 1% |
Other | 5 | 7% |
Unknown | 16 | 23% |