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Mendeley readers
Attention Score in Context
Title |
Heparan sulfate derived disaccharides in plasma and total urinary excretion of glycosaminoglycans correlate with disease severity in Sanfilippo disease
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Published in |
Journal of Inherited Metabolic Disease, September 2012
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DOI | 10.1007/s10545-012-9535-5 |
Pubmed ID | |
Authors |
J. de Ruijter, L. IJlst, W. Kulik, H. van Lenthe, T. Wagemans, N. van Vlies, F. A. Wijburg |
Abstract |
Sanfilippo disease (Mucopolysaccharidosis III) is a neurodegenerative lysosomal disorder characterized by accumulation of the glycosaminoglycan heparan sulfate (HS). MPS III has a large phenotypic variability and early assessment of disease severity is difficult. We investigated the correlation between disease severity and the plasma concentration of HS (pHS, defined by the sum of the heparan sulfate derived disaccharides obtained after enzymatic digestion) and urinary total GAGs level (uGAGs, measured by the dimethylene blue test) in a cross-sectional cohort of 44 MPS III patients. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Netherlands | 1 | 2% |
Unknown | 43 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 31% |
Student > Ph. D. Student | 11 | 24% |
Other | 4 | 9% |
Student > Master | 4 | 9% |
Student > Bachelor | 2 | 4% |
Other | 2 | 4% |
Unknown | 8 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 38% |
Biochemistry, Genetics and Molecular Biology | 6 | 13% |
Agricultural and Biological Sciences | 6 | 13% |
Business, Management and Accounting | 2 | 4% |
Chemistry | 2 | 4% |
Other | 5 | 11% |
Unknown | 7 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2013.
All research outputs
#15,251,053
of 22,678,224 outputs
Outputs from Journal of Inherited Metabolic Disease
#1,465
of 1,833 outputs
Outputs of similar age
#106,258
of 168,582 outputs
Outputs of similar age from Journal of Inherited Metabolic Disease
#14
of 19 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,833 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,582 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.