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Exposure to environmental factors increases connectivity between symptom domains in the psychopathology network

Overview of attention for article published in BMC Psychiatry, July 2016
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Title
Exposure to environmental factors increases connectivity between symptom domains in the psychopathology network
Published in
BMC Psychiatry, July 2016
DOI 10.1186/s12888-016-0935-1
Pubmed ID
Authors

Sinan Guloksuz, Martine van Nierop, Maarten Bak, Ron de Graaf, Margreet ten Have, Saskia van Dorsselaer, Nicole Gunther, Roselind Lieb, Ruud van Winkel, Hans-Ulrich Wittchen, Jim van Os

Abstract

We investigated to what degree environmental exposure (childhood trauma, urbanicity, cannabis use, and discrimination) impacts symptom connectivity using both continuous and categorical measures of psychopathology. Outcomes were continuous symptom dimensions of self-reported psychopathology using the Self-report Symptom Checklist-90-R in 3021 participants from The Early Developmental Stages of the Psychopathology (EDSP) study and binary DSM-III-R categories of mental disorders and a binary measure of psychotic symptoms in 7076 participants from The Netherlands Mental Health Survey and Incidence Study (NEMESIS-1). For each symptom dimension in the EDSP and mental disorder in the NEMESIS-1 as the dependent variable, regression analyses were carried out including each of the remaining symptom dimensions/mental disorders and its interaction with cumulative environmental risk load (the sum score of environmental exposures) as independent variables. All symptom dimensions in the EDSP and related diagnostic categories in the NEMESIS-1 were strongly associated with each other, and environmental exposures increased the degree of symptom connectivity in the networks in both cohorts. Our findings showing strong connectivity across symptom dimensions and related binary diagnostic constructs in two independent population cohorts provide further evidence for the conceptualization of psychopathology as a contextually sensitive network of mutually interacting symptoms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 139 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 15%
Researcher 19 14%
Student > Master 19 14%
Student > Bachelor 15 11%
Student > Doctoral Student 10 7%
Other 24 17%
Unknown 31 22%
Readers by discipline Count As %
Psychology 43 31%
Medicine and Dentistry 19 14%
Neuroscience 9 6%
Social Sciences 6 4%
Nursing and Health Professions 5 4%
Other 16 12%
Unknown 41 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2016.
All research outputs
#18,820,431
of 23,323,574 outputs
Outputs from BMC Psychiatry
#4,001
of 4,811 outputs
Outputs of similar age
#272,803
of 356,601 outputs
Outputs of similar age from BMC Psychiatry
#91
of 118 outputs
Altmetric has tracked 23,323,574 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
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