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Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function

Overview of attention for article published in PLOS ONE, September 2012
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Title
Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function
Published in
PLOS ONE, September 2012
DOI 10.1371/journal.pone.0045276
Pubmed ID
Authors

Lisa A. Humphries, Meredith H. Shaffer, Faruk Sacirbegovic, Tamar Tomassian, Kerrie-Ann McMahon, Patrick O. Humbert, Oscar Silva, June L. Round, Kogo Takamiya, Richard L. Huganir, Janis K. Burkhardt, Sarah M. Russell, M. Carrie Miceli

Abstract

The polarized reorganization of the T cell membrane and intracellular signaling molecules in response to T cell receptor (TCR) engagement has been implicated in the modulation of T cell development and effector responses. In siRNA-based studies Dlg1, a MAGUK scaffold protein and member of the Scribble polarity complex, has been shown to play a role in T cell polarity and TCR signal specificity, however the role of Dlg1 in T cell development and function in vivo remains unclear.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Germany 1 5%
Switzerland 1 5%
Unknown 17 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 15%
Student > Ph. D. Student 3 15%
Other 2 10%
Professor 2 10%
Librarian 2 10%
Other 4 20%
Unknown 4 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 30%
Immunology and Microbiology 4 20%
Biochemistry, Genetics and Molecular Biology 2 10%
Medicine and Dentistry 2 10%
Business, Management and Accounting 1 5%
Other 1 5%
Unknown 4 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2013.
All research outputs
#20,166,700
of 22,678,224 outputs
Outputs from PLOS ONE
#172,725
of 193,568 outputs
Outputs of similar age
#151,787
of 170,567 outputs
Outputs of similar age from PLOS ONE
#3,816
of 4,261 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,568 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,567 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,261 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.