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Animal Cell Technology: Products from Cells, Cells as Products

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Cover of 'Animal Cell Technology: Products from Cells, Cells as Products'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 Recombinant Pharmaceutical Protein Overexpression in an IRF-1 Proliferation Controlled Production System
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    Chapter 2 The Real Meaning of High Expression
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    Chapter 3 A Novel Mammalian Gene Regulation System Responsive to Streptogramin Antibiotics
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    Chapter 4 Feedback Control of Redox Potential in Hybridoma Cell Culture
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    Chapter 5 Genetic Manipulation of the Protein Synthetic Capacity of Mammalian Cells
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    Chapter 6 Retinoic Acid Enhances Monoclonal Antibody Production of Human-Human Hybridoma BD9
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    Chapter 7 Extracellular Adenosine 5’ Monophosphate Controls Proliferation and Stimulates Protein Production of rCHO Cells
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    Chapter 8 The Mode of Actions of Lysozyme as an Immunoglobul in Production Stimulating Factor (IPSF)
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    Chapter 9 A Dissection of Recombinant Protein Expression in CHO Cells Indicating Protein-Specific, not Cells Specific, Limitation
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    Chapter 10 Effect of Bioreactor Process Control Parameters on Apoptosis and Monoclonal Antibody Production During the Protein-Free Fed-Batch Culture of a Murine Myeloma
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    Chapter 11 Adenovirus Vector Production in 293 Fed-Batch Cultyres
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    Chapter 12 Influence of BCL-2 Over-Expression on NS0 and CHO Culture Viability and Chimeric Antibody Productivity
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    Chapter 13 A Regulatable Selective System Facilitating Isolation of High Expression Mammalian Cells
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    Chapter 14 Comparative Analysis of IRES Efficiency of Dicistronic Expression Vectors in Primary Cells and Permanent Cell Line
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    Chapter 15 Use of Gel Microdrops Selection System for Recombinant Cells
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    Chapter 16 Bovine Serum-Albumin with Grafted RGD Tailed Cyclic Peptudes as an Engineered Proadhesive Protein
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    Chapter 17 Matrix Attachment Regions in Stable CHO Cell Line Development
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    Chapter 18 High Cell Density Cultivation of Hybridoma Cells: Spin Filter vs Immobilized Culture
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    Chapter 19 Influence of the Inoculum on the Production of Antibodies with Mammalian Cells
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    Chapter 20 Establishing and Developing Cho Cell Lines for the Commercial Productoin of Human Anti-Rhesus D IgG
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    Chapter 21 Glucose and Glutamine Replacement for the Enhancement of Fed-Batch Processes Using CHO Cells
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    Chapter 22 Pilot Scale Production of Human Prothrombin Using a Recombinant CHO Cell Line
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    Chapter 23 Maintenance of High Viability During Direct Transition of CHO-K1 Cell Growth from 10% to 0% Serum; No Adaptation Required
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    Chapter 24 Analysis and Simultaneous Isolation of Recombinant t-PA Using High Performance Membrane Affinity Chromatography
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    Chapter 25 Improvement of the Primary Metabolism of Cell Cultures Introducing a Pyruvate Carboxylase Reaction Pathway
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    Chapter 26 Growth Kinetic Studies (In Hours) Based on the Fluorescence of Stable, GFP-Expressing CHO Cells
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    Chapter 27 Intracellular Localization of Non-Secreted Recombinant β-Trace Protein in Vesicle-Like Structures of Baculovirus-Infected Insect Cells
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    Chapter 28 Induction Kinetics of Apoptosis in Mammalian Cell Cultures
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    Chapter 29 A Model for the On-Line Scrutiny of Metabolism: Its Application to the Changing Nutritional Demands of Cultured Animal Cells
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    Chapter 30 Caspases as a Target for Apoptosis Inhibition in Hybridoma Cells in Culture
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    Chapter 31 Cell Activity After Cell Growth Inhibition by the IRF-1 System
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    Chapter 32 Establishment of a Pramary Liver Cell Culture from a Teleost, Oreochromis Mossambicus, the Tilapia: a Valid Tool for Physiological Studies
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    Chapter 33 TGF-β Induces Premature and Replicative Senescence in Cancer Cells
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    Chapter 34 Development of a Fed-batch Strategy That Utilizes Multiple Carbon Sources to Maximize Recombinant Protein Eepression in CHO Cells
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    Chapter 35 Development of a New, Highly Flexible, Fully Computer Integrated Fermentor Control System
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    Chapter 36 Cell Growth Rate Estimation in Packed-Bed and Hollow Fibers Bopreactprs: Metabolism and Productivity
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    Chapter 37 Influence of Oxygen Limitation on Myeloma Cell Cultures
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    Chapter 38 Comparison of Fed-batch Strategies in Hybridoma Cultures
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    Chapter 39 Non-Invasive Adaptive Control of the Feed Rate for High Cell Density CHO Cultures According to the pO2 Profile
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    Chapter 40 Cell Growth Control by the IRF-1 System in Perfusion Culture
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    Chapter 41 Modulation of Cell Cycle for Optimal Recombinant Protein Production
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    Chapter 42 Application of Bioassays for Suspended 293 Cell Enumerations in Chemically Defined Medium (CDM)
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    Chapter 43 Efficient Cell Growth by an Optimised Protein Free Medium Design and a Controlled Feeding Strategy
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    Chapter 44 Development of a Serum Free Meditum for a Human Diploid Fibroblast Cell Line
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    Chapter 45 The Use of Peptones as Medium Additives for High-Density Perfusion Cultures of Animal Cells
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    Chapter 46 Determination of Animal Cell Densities and Viabilities by the New Analyser CEDEX2
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    Chapter 47 Determination of Cell Numbers and Viability; Comparison of the Microcyte Flow Cytometer with Trypan Blue Counts and Coulter Counts
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    Chapter 48 Mid-Infrared Spectroscopic Monitoring of Animal Cell Culture Bioreactor Processes
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    Chapter 49 Mammalian Cell Monitoring Using the Microcyte Flow Cytometer
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    Chapter 50 Indirect Biomass Determination in Case of Con-Constant Metabolic Rates
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    Chapter 51 Whole Cell-Smart Microsensor: A first Approach Towards Interfacing Live Cells and Electronics
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    Chapter 52 Comparison of Immobilised Group Specific Affinity Ligands for the Bioseparation of Antibodies by High Performance Membrane Affinity Chromatography
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    Chapter 53 Posttranslational Modifications Limit High Level Expression of Functionally Active Chimeric P-Selectin Glycoprotein Ligand-1 in rCHO Cells
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    Chapter 54 Glycosylation Analysis of Nanomolar Amounts of Glycoprotein Combining In-gel Enzymatic Digestion and FACETM
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    Chapter 55 Glycosylation Patterns of a rec-Fusion Protein Expressed in BHK Cells at Different Metabolic States
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    Chapter 56 Elimination of N-Glycolylneuraminic Acid Residues in Recombinant Glycoproteins: A Gene Knock-Out Approach
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    Chapter 57 Fucosyltransferase III Production by Mammalian and Insect Cells for the Synthesis of Therapeutic Oligosaccharides
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    Chapter 58 Control of Therapeutic Monoclonal Antibody Glycosylation
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    Chapter 59 The Effect of Cell Line, Transfection Procedure and Reactor Conditions on the Glycosylation of Recombinant Human Anti-Rhesus D IgGl
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    Chapter 60 Metabolic Engineering of Recombinant Plasminogen Sialylation in Animal Cells by Tetracycline-Regulated Expression of Murine CMP-NeuAc Synthetase and Hamster CMP-NeuAc Transporter Genes
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    Chapter 61 Air-Trap-Technology: Bubble-Free Gas Transfer in Large Scale
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    Chapter 62 The Improvement of Aeration in 8000 I Animal Cell Culture Vessels
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    Chapter 63 A Novel Continuous Suspension Culture System for Hematopoietic Cells
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    Chapter 64 Large Scale Production of HIV-I gp120 Using Recombinant Vaccinia Virus in Packed-Bed Bioreactor
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    Chapter 65 The “Shear Tester”
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    Chapter 66 Membrane Oxygenation of Mammalian Cell Culture Fermenters Using Dupont Teflon AF-2400 Tubing
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    Chapter 67 Configuration of a Simple Dialysis Membrane Bioreactor Suitable for Large-Scale Application
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    Chapter 68 Erythropoietin Production from CHO Cells Grown in a Fluidized-Bed Bioreactor with Macroporous Beads
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    Chapter 69 Scale-Up of Fixed-Bed Reactors for the Cultivation of Animal Cells
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    Chapter 70 A Novel Conical Shaped Bioreactor for Small-Scale Investigations Under Defibed Conditions
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    Chapter 71 Continuous Perfused Fluidized Bed Technology
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    Chapter 72 Small Scale Bioreactor System for Process Development and Optimization
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    Chapter 73 Mammalian Transient Gene Expression-Potential, Practical Application and Perspectives
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    Chapter 74 Float! — And Express More
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    Chapter 75 Multiplicity and Time of Infection as Tools to Maximize Virus-Like Particle Production by Insect Cells
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    Chapter 76 Process Development for Transient Gene Expression in Mammalian Cells at The 3 L Scale: 10–50 MG of R-Protein in Days
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    Chapter 77 A Method to Determine the Optimal Time to Infect Insect Cells with the Baculovirus Expression System
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    Chapter 78 Analysis of Baculovirus Infected Sf9 Cells Using Flow Cytometry
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    Chapter 79 Adaptation of Recombinant HEK-293 Cells to Growth in Serum Free Suspension
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    Chapter 80 Growth on Microcarriers and Nutritional Needs of High Density Insect Cell Cultures
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    Chapter 81 Use of Flow Cytometry in the Evaluation of Hydroxyapatite for the Purification of Plasmid DNA
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    Chapter 82 Regulation and Standardi Sation of Gene Transfer Products in the European Union
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    Chapter 83 Study of Stability of Expression of a Humanized Monoclonal Antibody from a Transfected NSO Myeloma Cell Line Using Different Culture Media and Serum Concentrations
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    Chapter 84 Analysis of Alterations in Gene Expression after Amplification of Recombinant Genes in CHO Cells
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    Chapter 85 Stable Recombinant Expression and Functinal Identity of the Anti HIV-I Monoclonal Antibody 2F5 after IGG3/IGGI Subclass Switch in CHO-Cells
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    Chapter 86 Analysis of Genomic DNA and RNA-Transcripts of a Heterohybridoma SDNA imultanously Expressing IgG3 and IgG1 with Identical Specificity
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    Chapter 87 Tissue Engineering of a Bladder Wallpatch
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    Chapter 88 Integrated Optimization of Retrovirus Production for Gene Therapy
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    Chapter 89 Toxicological Evaluation of Surface Water Samples in Sensitized Cultured Fish Cells, and Comparison with the Microtox00AE; Method
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    Chapter 90 Electrolyzed and Natural Reduced Water Exhibit Insulin-Like Activity on Glucose Uptake into Muscle Cells and Adipocytes
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    Chapter 91 Study of DDS for a Cancer Therapy Applying Lipid Vesicle Immobilizing Eucheuma Serra Lectin
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    Chapter 92 Study of the Specific Binding between Lipid Vesicles and Human-Human Hybridoma toward Eitger DDS or Gene Transfection
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    Chapter 93 Suppression of Apoptosis in UV-Damaged Human Melanomacells by a Fermented Milk, Kefir
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    Chapter 94 Large Scale GMP Production of Retroviral Gene Therapy Vectors in Vert Low Serum Medium
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    Chapter 95 Chimeric Lyssavirus Glycoprotein: New Vector for Multivalent Vaccines
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    Chapter 96 The SPP Biotech Module 1: Proteins for Medical Applications a Multidisciplinary Effort for the Development of a Recombinant Anti-RhD Antibody Preparation of Hemolytic Disease of the Newborn
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    Chapter 97 Low Serum and Serum-Free Cultivation of Mammalian Cells Used for Virus Production Applications
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    Chapter 98 Development of a Serum-Free Medium for MRC-5 Culture
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    Chapter 99 Adaptation of Vero Cells to a Serum Free Medium for the Production of Rabies Virus
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    Chapter 100 Increased Productivity of a Rickettsia Vaccine: Enhancement of Adhesion Properties of Infected Endhothelial Cells by TGFβ
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    Chapter 101 Comparative Study of Cell Cultures Perspective for Rubella Virus Production
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    Chapter 102 Biogenesis of Epithelial Phenotype During Long-Term Cultivation of MDCK Cells in Serum-Free Ultra-MDCK Medium
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    Chapter 103 Sandwich Elisa Today: Limits for Sensitivity, Speed, Precision and Throughput
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    Chapter 104 Impact of ICH Guidelines on Phases of Development of Biotechnology Products
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    Chapter 105 The Microbial Risks of Xenotransplantation
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    Chapter 106 Cryopreservation under Protein-Free Medium Conditions: A Reliable Way to Safe Cell Banking
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    Chapter 107 Creation of Certified Cell Banks Suitable for Production of Healing and Immunobiological Preparations
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    Chapter 108 Endogeneous Retrovirus Particles and Their Eeffcts on the Growth Behavior of Hybridoma Cultivation Processes
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    Chapter 109 Testing for Adventitious Retroviruses Using PCR-Based Revese Transcriptase Assays
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    Chapter 110 Rapid RNA Quantitation from Xenotropic SP2/0 Retroviruses by Competitive RT-PCR ELISA
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    Chapter 111 Human Amniotic Epithelial (HAE) Cells Express Erythropoietin (EPO) and EPO-Receptor
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    Chapter 112 The Nordenau-Phenomenon—Facts and Hypotheses
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    Chapter 113 Conversion of a Process Development Pilot Plant into a Clinical Phase I/II Manufacturing Facility for Recombinant Proteins Expressed in Mammalian Cells
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    Chapter 114 Human Keratinocyte Culture on Macroporous Carries at the Air-Liquid Interface
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    Chapter 115 Comparison of Viability and Function of Primary Cells with Transformed Cellsfor use in a Bioartificial Liver Support System
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    Chapter 116 Determining Optimal Transport Conditions of In Vitro Cultured Human Chondrocytes Prepared for Autologous Re-Implantation Using Flow Cytometry
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    Chapter 117 Effects of Collagenase on Human Hematopoietic Cells
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    Chapter 118 Validation of the CACO-2 Test for Intestinal Permeability Assessment of Drugs: The Usefulness of PAPP, the Apparent Permeability Coefficient
Attention for Chapter 90: Electrolyzed and Natural Reduced Water Exhibit Insulin-Like Activity on Glucose Uptake into Muscle Cells and Adipocytes
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Chapter title
Electrolyzed and Natural Reduced Water Exhibit Insulin-Like Activity on Glucose Uptake into Muscle Cells and Adipocytes
Chapter number 90
Book title
Animal Cell Technology: Products from Cells, Cells as Products
Published by
Springer Netherlands, January 2002
DOI 10.1007/0-306-46875-1_90
Book ISBNs
978-0-7923-6075-9, 978-0-306-46875-9
Authors

M. Oda, K. Kusumoto, K. Teruya, T. Hara, T. Maki, S. Kabayama, Y. Katakura, K. Otsubo, S. Morisawa, H. Hayashi, Y. Ishii, S. Shirahata

Editors

A. Bernard, B. Griffiths, W. Noé, F. Wurm

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 40%
Lecturer 1 20%
Researcher 1 20%
Unknown 1 20%
Readers by discipline Count As %
Environmental Science 1 20%
Agricultural and Biological Sciences 1 20%
Chemistry 1 20%
Unknown 2 40%