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A Multi-Functional Synthetic Gene Network: A Frequency Multiplier, Oscillator and Switch

Overview of attention for article published in PLOS ONE, February 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
facebook
1 Facebook page

Citations

dimensions_citation
27 Dimensions

Readers on

mendeley
82 Mendeley
citeulike
4 CiteULike
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Title
A Multi-Functional Synthetic Gene Network: A Frequency Multiplier, Oscillator and Switch
Published in
PLOS ONE, February 2011
DOI 10.1371/journal.pone.0016140
Pubmed ID
Authors

Oliver Purcell, Mario di Bernardo, Claire S. Grierson, Nigel J. Savery

Abstract

We present the design and analysis of a synthetic gene network that performs frequency multiplication. It takes oscillatory transcription factor concentrations, such as those produced from the currently available genetic oscillators, as an input, and produces oscillations with half the input frequency as an output. Analysis of the bifurcation structure also reveals novel, programmable multi-functionality; in addition to functioning as a frequency multiplier, the network is able to function as a switch or an oscillator, depending on the temporal nature of the input. Multi-functionality is often observed in neuronal networks, where it is suggested to allow for the efficient coordination of different responses. This network represents a significant theoretical addition that extends the capabilities of synthetic gene networks.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
Spain 3 4%
United Kingdom 2 2%
Netherlands 1 1%
Brazil 1 1%
Belgium 1 1%
Unknown 71 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 28%
Researcher 20 24%
Student > Bachelor 10 12%
Student > Master 7 9%
Professor > Associate Professor 6 7%
Other 10 12%
Unknown 6 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 45%
Engineering 10 12%
Computer Science 9 11%
Biochemistry, Genetics and Molecular Biology 6 7%
Mathematics 5 6%
Other 9 11%
Unknown 6 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2014.
All research outputs
#3,666,156
of 22,678,224 outputs
Outputs from PLOS ONE
#45,314
of 193,568 outputs
Outputs of similar age
#17,763
of 105,898 outputs
Outputs of similar age from PLOS ONE
#343
of 1,284 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,568 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 105,898 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 1,284 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.