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Similar Pathogen Targets in Arabidopsis thaliana and Homo sapiens Protein Networks

Overview of attention for article published in PLOS ONE, September 2012
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Title
Similar Pathogen Targets in Arabidopsis thaliana and Homo sapiens Protein Networks
Published in
PLOS ONE, September 2012
DOI 10.1371/journal.pone.0045154
Pubmed ID
Authors

Paulo Shakarian, J. Kenneth Wickiser

Abstract

We study the behavior of pathogens on host protein networks for humans and Arabidopsis - noting striking similarities. Specifically, we preform [Formula: see text]-shell decomposition analysis on these networks - which groups the proteins into various "shells" based on network structure. We observe that shells with a higher average degree are more highly targeted (with a power-law relationship) and that highly targeted nodes lie in shells closer to the inner-core of the network. Additionally, we also note that the inner core of the network is significantly under-targeted. We show that these core proteins may have a role in intra-cellular communication and hypothesize that they are less attacked to ensure survival of the host. This may explain why certain high-degree proteins are not significantly attacked.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 50%
Researcher 1 17%
Student > Postgraduate 1 17%
Student > Master 1 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 83%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#15,251,053
of 22,678,224 outputs
Outputs from PLOS ONE
#129,864
of 193,568 outputs
Outputs of similar age
#107,207
of 170,728 outputs
Outputs of similar age from PLOS ONE
#2,724
of 4,259 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,568 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 4,259 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.