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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain
|
|---|---|
| Published in |
Virology Journal, September 2012
|
| DOI | 10.1186/1743-422x-9-215 |
| Pubmed ID | |
| Authors |
Byoung-Shik Shim, Konrad Stadler, Huan Huu Nguyen, Cheol-Heui Yun, Dong Wook Kim, Jun Chang, Cecil Czerkinsky, Man Ki Song |
| Abstract |
Sublingual (s.l.) administration of soluble protein antigens, inactivated viruses, or virus-like particles has been shown to induce broad immune responses in mucosal and extra-mucosal tissues. Recombinant replication-defective adenovirus vectors (rADVs) infect mucosa surface and therefore can serve as a mucosal antigen delivery vehicle. In this study we examined whether s.l. immunization with rADV encoding spike protein (S) (rADV-S) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) induces protective immunity against SARS-CoV and could serve as a safe mucosal route for delivery of rADV. |
X Demographics
The data shown below were collected from the profiles of 84 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 14 | 17% |
| United Kingdom | 4 | 5% |
| Australia | 3 | 4% |
| Brazil | 1 | 1% |
| Slovenia | 1 | 1% |
| Germany | 1 | 1% |
| France | 1 | 1% |
| Canada | 1 | 1% |
| China | 1 | 1% |
| Other | 2 | 2% |
| Unknown | 55 | 65% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 76 | 90% |
| Practitioners (doctors, other healthcare professionals) | 3 | 4% |
| Scientists | 3 | 4% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Korea, Republic of | 1 | 1% |
| Ireland | 1 | 1% |
| Unknown | 78 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 17% |
| Student > Ph. D. Student | 13 | 16% |
| Student > Master | 12 | 15% |
| Student > Bachelor | 8 | 10% |
| Student > Postgraduate | 4 | 5% |
| Other | 16 | 20% |
| Unknown | 14 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 12 | 15% |
| Biochemistry, Genetics and Molecular Biology | 11 | 14% |
| Medicine and Dentistry | 11 | 14% |
| Agricultural and Biological Sciences | 10 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
| Other | 14 | 17% |
| Unknown | 19 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 58. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2023.
All research outputs
#722,091
of 25,318,210 outputs
Outputs from Virology Journal
#62
of 3,382 outputs
Outputs of similar age
#3,701
of 179,154 outputs
Outputs of similar age from Virology Journal
#2
of 104 outputs
Altmetric has tracked 25,318,210 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,382 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,154 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.