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Psychological stress in early life as a predisposing factor for the development of chronic pain: Clinical and preclinical evidence and neurobiological mechanisms

Overview of attention for article published in Journal of Neuroscience Research, July 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 3,166)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
44 news outlets
blogs
1 blog
twitter
88 tweeters
facebook
11 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
89 Dimensions

Readers on

mendeley
240 Mendeley
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Title
Psychological stress in early life as a predisposing factor for the development of chronic pain: Clinical and preclinical evidence and neurobiological mechanisms
Published in
Journal of Neuroscience Research, July 2016
DOI 10.1002/jnr.23802
Pubmed ID
Authors

Nikita N. Burke, David P. Finn, Brian E. McGuire, Michelle Roche

Abstract

A wealth of research over the past 2 decades has expanded our understanding of the impact of early-life adversity on physiological function and, consequently, health and wellbeing in later life. Early-life adversity increases the risk of developing a number of disorders, such as chronic pain, fibromyalgia, and irritable bowel syndrome. Although much of the research has examined the impact of physical maltreatment, an increasing number of studies have been published over the past few years examining the effect of childhood psychological stress and trauma on the development of various types of chronic pain conditions. We review the clinical and preclinical data examining the link among early-life psychological stress, altered nociceptive behavior, and chronic pain in later life. Evidence supporting a role for certain key neurobiological substrates, including the hypothalamic-pituitary-adrenal axis; monoaminergic, opioidergic, endocannabinoid and immune systems; and epigenetic mechanisms in the association between early-life psychological stress and chronic pain, is provided. Greater understanding of the impact of early-life stress may inform the development of personalized treatments for chronic pain in later life and strategies to prevent its onset in susceptible individuals. © 2016 Wiley Periodicals, Inc.

Twitter Demographics

The data shown below were collected from the profiles of 88 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 1 <1%
Switzerland 1 <1%
Unknown 238 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 48 20%
Student > Master 40 17%
Student > Ph. D. Student 32 13%
Researcher 27 11%
Student > Doctoral Student 22 9%
Other 43 18%
Unknown 28 12%
Readers by discipline Count As %
Psychology 56 23%
Medicine and Dentistry 38 16%
Neuroscience 27 11%
Nursing and Health Professions 26 11%
Agricultural and Biological Sciences 15 6%
Other 34 14%
Unknown 44 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 416. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2019.
All research outputs
#38,425
of 17,729,196 outputs
Outputs from Journal of Neuroscience Research
#2
of 3,166 outputs
Outputs of similar age
#1,156
of 266,285 outputs
Outputs of similar age from Journal of Neuroscience Research
#1
of 27 outputs
Altmetric has tracked 17,729,196 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,166 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,285 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.