Title |
Genome-wide expressions in autologous eutopic and ectopic endometrium of fertile women with endometriosis
|
---|---|
Published in |
Reproductive Biology and Endocrinology, September 2012
|
DOI | 10.1186/1477-7827-10-84 |
Pubmed ID | |
Authors |
Meraj A Khan, Jayasree Sengupta, Suneeta Mittal, Debabrata Ghosh |
Abstract |
In order to obtain a lead of the pathophysiology of endometriosis, genome-wide expressional analyses of eutopic and ectopic endometrium have earlier been reported, however, the effects of stages of severity and phases of menstrual cycle on expressional profiles have not been examined. The effect of genetic heterogeneity and fertility history on transcriptional activity was also not considered. In the present study, a genome-wide expression analysis of autologous, paired eutopic and ectopic endometrial samples obtained from fertile women (n=18) suffering from moderate (stage 3; n=8) or severe (stage 4; n=10) ovarian endometriosis during proliferative (n=13) and secretory (n=5) phases of menstrual cycle was performed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 55 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 16% |
Researcher | 7 | 12% |
Student > Postgraduate | 7 | 12% |
Student > Bachelor | 6 | 11% |
Other | 6 | 11% |
Other | 12 | 21% |
Unknown | 10 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 32% |
Agricultural and Biological Sciences | 10 | 18% |
Biochemistry, Genetics and Molecular Biology | 6 | 11% |
Psychology | 2 | 4% |
Chemical Engineering | 1 | 2% |
Other | 5 | 9% |
Unknown | 15 | 26% |