Title |
Improving Antibiotic Activity against Wound Pathogens with Manuka Honey In Vitro
|
---|---|
Published in |
PLOS ONE, September 2012
|
DOI | 10.1371/journal.pone.0045600 |
Pubmed ID | |
Authors |
Rowena Jenkins, Rose Cooper |
Abstract |
Following the discovery of synergistic action between oxacillin and manuka honey against methicillin-resistant Staphylococcus aureus, this study was undertaken to search for further synergistic combinations of antibiotics and honey that might have potential in treating wounds. Fifteen antibiotics were tested with and without sublethal concentrations of manuka honey against each of MRSA and Pseudomonas aeruginosa using disc diffusion, broth dilution, E strip, chequerboard titration and growth curves. Five novel antibiotic and manuka honey combinations were found that improved antibacterial effectiveness in vitro and these offer a new avenue of future topical treatments for wound infections caused by these two important pathogens. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Russia | 2 | 33% |
United States | 1 | 17% |
Italy | 1 | 17% |
New Zealand | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 83% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Ecuador | 1 | <1% |
Canada | 1 | <1% |
Unknown | 146 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 40 | 27% |
Student > Ph. D. Student | 20 | 13% |
Student > Master | 15 | 10% |
Researcher | 9 | 6% |
Other | 9 | 6% |
Other | 19 | 13% |
Unknown | 37 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 34 | 23% |
Medicine and Dentistry | 23 | 15% |
Immunology and Microbiology | 14 | 9% |
Biochemistry, Genetics and Molecular Biology | 9 | 6% |
Nursing and Health Professions | 5 | 3% |
Other | 21 | 14% |
Unknown | 43 | 29% |