Of course, a phenomenon resembling the Crabtree effect does occur in human cells and tissues, although it may be as simple as the ATP free energy reserve becoming "topped up" from glycolysis, slowing OxPhos activity, i.e., the force-flow relationship. 6/n
@ElworthyStone Yep, live cells.. Phototoxicity can be an issue! The photo efficiency of non-quenching TMRM is quite good though, and I'm able to use 0.2-0.5% laser power typically. Morphology can be difficult to quantify. I've used cluster entropy in the p
RT @CAS_mitolab: Curious to know if mitochondrial network complexity correlates with adaptive changes in function? It didn't in these exper…