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X Demographics
Mendeley readers
Attention Score in Context
| Title |
N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor
|
|---|---|
| Published in |
PLOS ONE, October 2012
|
| DOI | 10.1371/journal.pone.0046039 |
| Pubmed ID | |
| Authors |
Yaozhong Zou, William I. Weis, Brian K. Kobilka |
| Abstract |
A highly crystallizable T4 lysozyme (T4L) was fused to the N-terminus of the β(2) adrenergic receptor (β(2)AR), a G-protein coupled receptor (GPCR) for catecholamines. We demonstrate that the N-terminal fused T4L is sufficiently rigid relative to the receptor to facilitate crystallogenesis without thermostabilizing mutations or the use of a stabilizing antibody, G protein, or protein fused to the 3rd intracellular loop. This approach adds to the protein engineering strategies that enable crystallographic studies of GPCRs alone or in complex with a signaling partner. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 12% |
| United Kingdom | 2 | 8% |
| Indonesia | 1 | 4% |
| Guatemala | 1 | 4% |
| Australia | 1 | 4% |
| Peru | 1 | 4% |
| France | 1 | 4% |
| Chile | 1 | 4% |
| Canada | 1 | 4% |
| Other | 3 | 12% |
| Unknown | 10 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 72% |
| Scientists | 6 | 24% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 261 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| United Kingdom | 2 | <1% |
| Denmark | 2 | <1% |
| Austria | 2 | <1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| France | 1 | <1% |
| Unknown | 248 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 65 | 25% |
| Researcher | 61 | 23% |
| Student > Master | 35 | 13% |
| Student > Doctoral Student | 20 | 8% |
| Student > Bachelor | 19 | 7% |
| Other | 36 | 14% |
| Unknown | 25 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 96 | 37% |
| Biochemistry, Genetics and Molecular Biology | 78 | 30% |
| Chemistry | 31 | 12% |
| Medicine and Dentistry | 6 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 2% |
| Other | 15 | 6% |
| Unknown | 30 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2024.
All research outputs
#1,185,760
of 24,143,470 outputs
Outputs from PLOS ONE
#15,397
of 207,525 outputs
Outputs of similar age
#6,957
of 175,312 outputs
Outputs of similar age from PLOS ONE
#252
of 4,544 outputs
Altmetric has tracked 24,143,470 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 207,525 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,312 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 4,544 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.