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Evaluation of Phenolic Phytochemical Enriched Commercial Plant Extracts on the In Vitro Inhibition of α-Glucosidase

Overview of attention for article published in Frontiers in Nutrition, November 2017
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Title
Evaluation of Phenolic Phytochemical Enriched Commercial Plant Extracts on the In Vitro Inhibition of α-Glucosidase
Published in
Frontiers in Nutrition, November 2017
DOI 10.3389/fnut.2017.00056
Pubmed ID
Authors

Allie Brown, Danielle Anderson, Kenneth Racicot, Sarah J. Pilkenton, Emmanouil Apostolidis

Abstract

Green tea (GT), cranberry (CR), and tart cherry extracts were evaluated for their ability to inhibit yeast α-glucosidase, relevant to glucose uptake. The total phenolic content (TPC), antioxidant activity, and in vitro inhibitory activity of yeast α-glucosidase were examined for the extracts in the present study. GT had higher TPC and antioxidant activity, but CR demonstrated a greater α-glucosidase inhibitory activity, on phenolic basis. CR was fractionated using LH-20 column chromatography into two fractions: 30% methanol (CME) and 70% acetone (CAE). TPC, antioxidant activity, and yeast α-glucosidase inhibitory activity were determined for the fractions. CAE had a greater TPC and antioxidant activity than CME, but the two fractions had a synergistic effect when inhibiting yeast α-glucosidase. Our findings suggest that CR has the greatest potential to possibly manage post-prandial blood glucose levels via the inhibition of α-glucosidase, and that the effect is through synergistic activity of the extract's phenolic compounds.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 17%
Student > Doctoral Student 4 11%
Student > Bachelor 4 11%
Student > Master 2 6%
Researcher 2 6%
Other 2 6%
Unknown 15 43%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 26%
Biochemistry, Genetics and Molecular Biology 2 6%
Immunology and Microbiology 2 6%
Chemistry 2 6%
Nursing and Health Professions 1 3%
Other 3 9%
Unknown 16 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2017.
All research outputs
#14,958,596
of 23,007,887 outputs
Outputs from Frontiers in Nutrition
#2,256
of 4,661 outputs
Outputs of similar age
#194,317
of 328,166 outputs
Outputs of similar age from Frontiers in Nutrition
#19
of 23 outputs
Altmetric has tracked 23,007,887 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,661 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,166 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.