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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Impact of resistance exercise on ribosome biogenesis is acutely regulated by post‐exercise recovery strategies
|
|---|---|
| Published in |
Physiological Reports, January 2016
|
| DOI | 10.14814/phy2.12670 |
| Pubmed ID | |
| Authors |
Vandré C. Figueiredo, Llion A. Roberts, James F. Markworth, Matthew P. G. Barnett, Jeff S. Coombes, Truls Raastad, Jonathan M. Peake, David Cameron‐Smith |
| Abstract |
Muscle hypertrophy occurs following increased protein synthesis, which requires activation of the ribosomal complex. Additionally, increased translational capacity via elevated ribosomal RNA (rRNA) synthesis has also been implicated in resistance training-induced skeletal muscle hypertrophy. The time course of ribosome biogenesis following resistance exercise (RE) and the impact exerted by differing recovery strategies remains unknown. In the present study, the activation of transcriptional regulators, the expression levels of pre-rRNA, and mature rRNA components were measured through 48 h after a single-bout RE. In addition, the effects of either low-intensity cycling (active recovery, ACT) or a cold-water immersion (CWI) recovery strategy were compared. Nine male subjects performed two bouts of high-load RE randomized to be followed by 10 min of either ACT or CWI. Muscle biopsies were collected before RE and at 2, 24, and 48 h after RE. RE increased the phosphorylation of the p38-MNK1-eIF4E axis, an effect only evident with ACT recovery. Downstream, cyclin D1 protein, total eIF4E, upstream binding factor 1 (UBF1), and c-Myc proteins were all increased only after RE with ACT. This corresponded with elevated abundance of the pre-rRNAs (45S, ITS-28S, ITS-5.8S, and ETS-18S) from 24 h after RE with ACT. In conclusion, coordinated upstream signaling and activation of transcriptional factors stimulated pre-rRNA expression after RE. CWI, as a recovery strategy, markedly blunted these events, suggesting that suppressed ribosome biogenesis may be one factor contributing to the impaired hypertrophic response observed when CWI is used regularly after exercise. |
X Demographics
The data shown below were collected from the profiles of 112 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 22 | 20% |
| United Kingdom | 13 | 12% |
| Spain | 7 | 6% |
| Australia | 6 | 5% |
| Brazil | 6 | 5% |
| Japan | 5 | 4% |
| Canada | 3 | 3% |
| India | 2 | 2% |
| Sweden | 2 | 2% |
| Other | 16 | 14% |
| Unknown | 30 | 27% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 67 | 60% |
| Scientists | 31 | 28% |
| Practitioners (doctors, other healthcare professionals) | 11 | 10% |
| Science communicators (journalists, bloggers, editors) | 3 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 179 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Brazil | 1 | <1% |
| France | 1 | <1% |
| Japan | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 173 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 16% |
| Student > Bachelor | 26 | 15% |
| Student > Ph. D. Student | 22 | 12% |
| Researcher | 17 | 9% |
| Student > Doctoral Student | 11 | 6% |
| Other | 37 | 21% |
| Unknown | 38 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 46 | 26% |
| Medicine and Dentistry | 24 | 13% |
| Biochemistry, Genetics and Molecular Biology | 21 | 12% |
| Agricultural and Biological Sciences | 15 | 8% |
| Nursing and Health Professions | 11 | 6% |
| Other | 17 | 9% |
| Unknown | 45 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 69. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2022.
All research outputs
#615,868
of 25,310,061 outputs
Outputs from Physiological Reports
#57
of 2,888 outputs
Outputs of similar age
#11,210
of 409,200 outputs
Outputs of similar age from Physiological Reports
#2
of 51 outputs
Altmetric has tracked 25,310,061 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,888 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 409,200 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.