Title |
Autistic Traits Below the Clinical Threshold: Re-examining the Broader Autism Phenotype in the 21st Century
|
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Published in |
Neuropsychology Review, October 2011
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DOI | 10.1007/s11065-011-9183-9 |
Pubmed ID | |
Authors |
E. Sucksmith, I. Roth, R. A. Hoekstra |
Abstract |
Diagnosis, intervention and support for people with autism can be assisted by research into the aetiology of the condition. Twin and family studies indicate that autism spectrum conditions are highly heritable; genetic relatives of people with autism often show milder expression of traits characteristic for autism, referred to as the Broader Autism Phenotype (BAP). In the past decade, advances in the biological and behavioural sciences have facilitated a more thorough examination of the BAP from multiple levels of analysis. Here, the candidate phenotypic traits delineating the BAP are summarised, including key findings from neuroimaging studies examining the neural substrates of the BAP. We conclude by reviewing the value of further research into the BAP, with an emphasis on deriving heritable endophenotypes which will reliably index autism susceptibility and offer neurodevelopmental mechanisms that bridge the gap between genes and a clinical autism diagnosis. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 1% |
United Kingdom | 4 | 1% |
Mexico | 2 | <1% |
Germany | 1 | <1% |
Italy | 1 | <1% |
Canada | 1 | <1% |
Unknown | 375 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 59 | 15% |
Student > Master | 53 | 14% |
Student > Bachelor | 45 | 12% |
Student > Doctoral Student | 34 | 9% |
Researcher | 31 | 8% |
Other | 75 | 19% |
Unknown | 92 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 184 | 47% |
Medicine and Dentistry | 24 | 6% |
Neuroscience | 16 | 4% |
Social Sciences | 15 | 4% |
Agricultural and Biological Sciences | 13 | 3% |
Other | 31 | 8% |
Unknown | 106 | 27% |