The nature of ligand efficiency
Computational Chemistry Daily,
jcheminf.biomedcentral.com - Ligand efficiency is a widely used design parameter in drug discovery. It is calculated by scaling…
jcheminf.biomedcentral.com - Ligand efficiency is a widely used design parameter in drug discovery. It is calculated by scaling…
Paramin panoramaCrystallographic fragment screens have been run recently against the main protease (at Diamond) and the Nsp3…
I'll examine an article entitled ‘Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations’ (YL2018…
Regular readers of this blog will know that I have an interest, which some might term an obsession, with units. At high school…