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Pharmacokinetic profile of a 24-hour controlled-release OROS® formulation of hydromorphone in the presence and absence of food

Overview of attention for article published in BMC Clinical Pharmacology, February 2007
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Title
Pharmacokinetic profile of a 24-hour controlled-release OROS® formulation of hydromorphone in the presence and absence of food
Published in
BMC Clinical Pharmacology, February 2007
DOI 10.1186/1472-6904-7-2
Pubmed ID
Authors

Gayatri Sathyan, Emily Xu, John Thipphawong, Suneel K Gupta

Abstract

The objective of this study was to compare the pharmacokinetic profile of a novel, once-daily, controlled-release formulation of hydromorphone (OROS hydromorphone) under fasting conditions with that immediately after a high-fat breakfast in healthy volunteers. The effect of the opioid antagonist naltrexone on fasting hydromorphone pharmacokinetics also was evaluated.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Norway 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 18%
Student > Ph. D. Student 3 14%
Student > Master 3 14%
Other 2 9%
Student > Postgraduate 2 9%
Other 6 27%
Unknown 2 9%
Readers by discipline Count As %
Medicine and Dentistry 8 36%
Pharmacology, Toxicology and Pharmaceutical Science 3 14%
Biochemistry, Genetics and Molecular Biology 2 9%
Psychology 2 9%
Agricultural and Biological Sciences 2 9%
Other 3 14%
Unknown 2 9%