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Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study

Overview of attention for article published in European Journal of Epidemiology, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

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2 news outlets
twitter
8 X users
facebook
2 Facebook pages

Citations

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50 Dimensions

Readers on

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138 Mendeley
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1 CiteULike
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Title
Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study
Published in
European Journal of Epidemiology, March 2016
DOI 10.1007/s10654-016-0119-9
Pubmed ID
Authors

Valentina Gallo, Nicola Vanacore, H. Bas Bueno-de-Mesquita, Roel Vermeulen, Carol Brayne, Neil Pearce, Petra A. Wark, Heather A. Ward, Pietro Ferrari, Mazda Jenab, Peter M. Andersen, Patrik Wennberg, Nicholas Wareham, Verena Katzke, Rudolf Kaaks, Elisabete Weiderpass, Petra H. Peeters, Amalia Mattiello, Valeria Pala, Aurelio Barricante, Maria-Dolores Chirlaque, Noémie Travier, Ruth C. Travis, Maria-Jose Sanchez, Hélène Pessah-Rasmussen, Jesper Petersson, Anne Tjønneland, Rosario Tumino, Jose Ramon Quiros, Antonia Trichopoulou, Andreas Kyrozis, Despoina Oikonomidou, Giovanna Masala, Carlotta Sacerdote, Larraitz Arriola, Heiner Boeing, Matthaeus Vigl, Francoise Claver-Chapelon, Lefkos Middleton, Elio Riboli, Paolo Vineis

Abstract

Previous case-control studies have suggested a possible increased risk of Amyotrophic Lateral Sclerosis (ALS) with physical activity (PA), but this association has never been studied in prospective cohort studies. We therefore assessed the association between PA and risk of death from ALS in the European Prospective Investigation into Cancer and Nutrition. A total of 472,100 individuals were included in the analysis, yielding 219 ALS deaths. At recruitment, information on PA was collected thorough standardised questionnaires. Total PA was expressed by the Cambridge Physical Activity Index (CPAI) and analysed in relation to ALS mortality, using Cox hazard models. Interactions with age, sex, and anthropometric measures were assessed. Total PA was weakly inversely associated with ALS mortality with a borderline statistically significant trend across categories (p = 0.042), with those physically active being 33 % less likely to die from ALS compared to those inactive: HR = 0.67 (95 % CI 0.42-1.06). Anthropometric measures, sex, and age did not modify the association with CPAI. The present study shows a slightly decreased-not increased like in case-control studies-risk of dying from ALS in those with high levels of total PA at enrolment. This association does not appear confounded by age, gender, anthropometry, smoking, and education. Ours was the first prospective cohort study on ALS and physical activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 138 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 15%
Student > Ph. D. Student 20 14%
Student > Bachelor 17 12%
Student > Master 8 6%
Student > Postgraduate 7 5%
Other 25 18%
Unknown 40 29%
Readers by discipline Count As %
Medicine and Dentistry 32 23%
Neuroscience 12 9%
Biochemistry, Genetics and Molecular Biology 9 7%
Nursing and Health Professions 8 6%
Agricultural and Biological Sciences 5 4%
Other 24 17%
Unknown 48 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2021.
All research outputs
#1,354,713
of 22,856,968 outputs
Outputs from European Journal of Epidemiology
#195
of 1,629 outputs
Outputs of similar age
#24,280
of 299,532 outputs
Outputs of similar age from European Journal of Epidemiology
#2
of 23 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,629 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,532 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.