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Mendeley readers
| Chapter title |
Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells
|
|---|---|
| Chapter number | 1 |
| Book title |
HDAC/HAT Function Assessment and Inhibitor Development
|
| Published in |
Methods in molecular biology, January 2017
|
| DOI | 10.1007/978-1-4939-6527-4_1 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6525-0, 978-1-4939-6527-4
|
| Authors |
Anja Göder, Nisintha Mahendrarajah, Oliver H. Krämer |
| Abstract |
Autophagy is a lysosome-dependent, intracellular pathway for the recycling of cellular components. It plays a pivotal role in both cancer development and the response to chemotherapy. Here we describe how autophagy can be monitored in living cells by flow cytometry using the cationic amphiphilic tracer dye Cyto-ID(®) Green. The detection of autophagy induction in the human leukemia cell line K562 after the treatment with the HDAC class I inhibitor MS-275 serves as an example for this approach. |
Mendeley readers
The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 50% |
| Professor | 1 | 25% |
| Student > Master | 1 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 50% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 25% |
| Unknown | 1 | 25% |