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Efficacy of acemannan in treatment of canine and feline spontaneous neoplasms.

Overview of attention for article published in Molecular biotherapy, December 1991
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3 Wikipedia pages

Citations

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16 Mendeley
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Title
Efficacy of acemannan in treatment of canine and feline spontaneous neoplasms.
Published in
Molecular biotherapy, December 1991
Pubmed ID
Authors

C Harris, K Pierce, G King, K M Yates, J Hall, I Tizard

Abstract

Forty-three dogs and cats with spontaneous tumors were treated with the immunostimulating polysaccharide acemannan by intraperitoneal and intralesional routes of administration. Tumors from 26 of these animals showed histopathological evidence of immunological attack as shown by marked necrosis or lymphocytic infiltration. Thirteen showed moderate to marked tumor necrosis or liquefaction. Twenty-one demonstrated lymphoid infiltration, and seven demonstrated encapsulation. Twelve animals showed obvious clinical improvement as assessed by tumor shrinkage, tumor necrosis, or prolonged survival; these included five of seven animals with fibrosarcomas. It is believed that acemannan exerts its antitumor activity through macrophage activation and the release of tumor necrosis factor, interleukin-1, and interferon.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 25%
Student > Ph. D. Student 3 19%
Student > Doctoral Student 1 6%
Other 1 6%
Lecturer 1 6%
Other 1 6%
Unknown 5 31%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 3 19%
Agricultural and Biological Sciences 2 13%
Medicine and Dentistry 2 13%
Computer Science 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Other 0 0%
Unknown 7 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2020.
All research outputs
#8,537,346
of 25,377,790 outputs
Outputs from Molecular biotherapy
#2
of 5 outputs
Outputs of similar age
#12,389
of 61,554 outputs
Outputs of similar age from Molecular biotherapy
#1
of 1 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5 research outputs from this source. They receive a mean Attention Score of 3.0. This one scored the same or higher as 3 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,554 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them