Title |
COVID-19 and Anemia: What Do We Know So Far?
|
---|---|
Published in |
Hemoglobin, July 2023
|
DOI | 10.1080/03630269.2023.2236546 |
Pubmed ID | |
Authors |
Luai Abu-Ismail, Mohammad J. J. Taha, Mohammad T. Abuawwad, Yaqeen Al-Bustanji, Khayry Al-Shami, Abdulqadir Nashwan, Mohamed Yassin |
Abstract |
On 11 March 2020, the World Health Organization (WHO) declared the novel SARS-CoV-2 virus responsible for causing COVID-19, a global pandemic. The virus primarily targets the respiratory system but can also affect other systems, notably causing hematological pathologies. Anemia, a common hematologic disorder, is characterized by the reduced oxygen-carrying capacity of red blood cells. The existing literature has a suspected link between anemia and severe COVID-19 cases. Researchers are currently investigating the long-term complications of COVID-19 in anemic patients, as these complications may play a crucial role in predicting patient prognosis. Anemic individuals are at a higher risk of experiencing severe COVID-19 infections due to several contributing pathophysiological mechanisms, including thrombotic, hemorrhagic, and autoimmune etiologies. The primary effect of these mechanisms is a decrease in circulating hemoglobin levels, reducing oxygen availability for cells. This exacerbates the hypoxia caused by COVID-19-induced acute respiratory distress syndrome (ARDS). This review offers a comprehensive overview of the evidence regarding the long-term complications of COVID-19 in anemic patients. |
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Other | 1 | 5% |
Unknown | 12 | 55% |
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Biochemistry, Genetics and Molecular Biology | 3 | 14% |
Computer Science | 1 | 5% |
Unknown | 13 | 59% |