| Chapter title |
Aquaporins in Urinary System
|
|---|---|
| Chapter number | 9 |
| Book title |
Aquaporins
|
| Published in |
Advances in experimental medicine and biology, March 2017
|
| DOI | 10.1007/978-94-024-1057-0_9 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-241055-6, 978-9-40-241057-0
|
| Authors |
Yingjie Li M.S., Weiling Wang Ph.D., Tao Jiang M.D., Baoxue Yang M.D., Ph.D., Yingjie Li, Weiling Wang, Tao Jiang, Baoxue Yang |
| Editors |
Baoxue Yang |
| Abstract |
Several aquaporin (AQP )-type water channels are expressed in kidney: AQP1 in the proximal tubule, thin descending limb of Henle, and vasa recta; AQP2 -6 in the collecting duct; AQP7 in the proximal tubule; AQP8 in the proximal tubule and collecting duct; and AQP11 in the endoplasmic reticulum of proximal tubule cells. AQP2 is the vasopressin-regulated water channel that is important in hereditary and acquired diseases affecting urine-concentrating ability. The roles of AQPs in renal physiology and transepithelial water transport have been determined using AQP knockout mouse models. This chapter describes renal physiologic insights revealed by phenotypic analysis of AQP knockout mice and the prospects for further basic and clinical studies. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Czechia | 1 | 4% |
| Unknown | 26 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 26% |
| Student > Bachelor | 5 | 19% |
| Student > Ph. D. Student | 4 | 15% |
| Student > Master | 3 | 11% |
| Student > Doctoral Student | 1 | 4% |
| Other | 0 | 0% |
| Unknown | 7 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 33% |
| Medicine and Dentistry | 4 | 15% |
| Agricultural and Biological Sciences | 3 | 11% |
| Nursing and Health Professions | 1 | 4% |
| Immunology and Microbiology | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 8 | 30% |