Title |
Comprehensive discovery and characterization of small RNAs in Corynebacterium glutamicumATCC 13032
|
---|---|
Published in |
BMC Genomics, October 2013
|
DOI | 10.1186/1471-2164-14-714 |
Pubmed ID | |
Authors |
Almut Mentz, Armin Neshat, Katharina Pfeifer-Sancar, Alfred Pühler, Christian Rückert, Jörn Kalinowski |
Abstract |
Recent discoveries on bacterial transcriptomes gave evidence that small RNAs (sRNAs) have important regulatory roles in prokaryotic cells. Modern high-throughput sequencing approaches (RNA-Seq) enable the most detailed view on transcriptomes offering an unmatched comprehensiveness and single-base resolution. Whole transcriptome data obtained by RNA-Seq can be used to detect and characterize all transcript species, including small RNAs. Here, we describe an RNA-Seq approach for comprehensive detection and characterization of small RNAs from Corynebacterium glutamicum, an actinobacterium of high industrial relevance and model organism for medically important Corynebacterianeae, such as C. diphtheriae and Mycobacterium tuberculosis. |
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France | 1 | 25% |
Unknown | 2 | 50% |
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Members of the public | 1 | 25% |
Mendeley readers
Geographical breakdown
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China | 1 | <1% |
Germany | 1 | <1% |
Unknown | 101 | 98% |
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Student > Ph. D. Student | 30 | 29% |
Researcher | 23 | 22% |
Student > Master | 14 | 14% |
Student > Bachelor | 13 | 13% |
Student > Doctoral Student | 3 | 3% |
Other | 7 | 7% |
Unknown | 13 | 13% |
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Immunology and Microbiology | 4 | 4% |
Computer Science | 3 | 3% |
Other | 4 | 4% |
Unknown | 15 | 15% |