Chapter title |
Recovery from Chronic Diseases of Consciousness: State of the Art in Neuromodulation for Persistent Vegetative State and Minimally Conscious State
|
---|---|
Chapter number | 4 |
Book title |
Trends in Reconstructive Neurosurgery
|
Published in |
Acta neurochirurgica Supplement, January 2017
|
DOI | 10.1007/978-3-319-39546-3_4 |
Pubmed ID | |
Book ISBNs |
978-3-31-939545-6, 978-3-31-939546-3
|
Authors |
Pier Paolo Mattogno, Giuseppe Barbagallo, Gerardo Iacopino, Gaetano Pappalardo, Giuseppe LA Rocca, Francesco Signorelli, Jun Zhong, Massimiliano Visocchi |
Abstract |
Chronic diseases of consciousness (CDC) can still be considered a challenging frontier for modern medicine, probably because of their not completely understood physiopathological mechanisms. Following encouraging evidence on cerebral hemodynamics, some authors have hypothesized a role for neuromodulation in the treatment of CDC patients. In the past 40 years, spinal cord stimulation (SCS) and deep brain stimulation (DBS) have been used experimentally for the treatment of patients in a severe altered state of consciousness, with some interesting but not conclusive results. The present review summarizes the data currently available in the literature on this particular and debated topic. On these grounds, further clinical studies are needed to better understand the altered dynamics of neuronal network circuits in CDC patients as a step towards novel therapeutic strategies. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 18% |
Researcher | 2 | 12% |
Professor | 2 | 12% |
Student > Doctoral Student | 1 | 6% |
Student > Bachelor | 1 | 6% |
Other | 4 | 24% |
Unknown | 4 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 29% |
Neuroscience | 3 | 18% |
Psychology | 2 | 12% |
Immunology and Microbiology | 1 | 6% |
Mathematics | 1 | 6% |
Other | 0 | 0% |
Unknown | 5 | 29% |