Chapter title |
Management of Cerebral Radiation Necrosis: A Retrospective Study of 12 Patients
|
---|---|
Chapter number | 30 |
Book title |
Trends in Reconstructive Neurosurgery
|
Published in |
Acta neurochirurgica Supplement, January 2017
|
DOI | 10.1007/978-3-319-39546-3_30 |
Pubmed ID | |
Book ISBNs |
978-3-31-939545-6, 978-3-31-939546-3
|
Authors |
Chenlong Liao, Massimiliano Visocchi, Wenchuan Zhang, Min Yang, Wenxiang Zhong, Pengfei Liu |
Abstract |
Cerebral radiation necrosis (RN) is a severe complication of radiotherapy for cerebral pathologies. This study discusses the radiographic and pathological features of 12 patients with RN and investigates the management strategy. Eleven patients with brain tumors, and one with cerebral cavernous angioma, treated by surgical resection or Gamma Knife alone before radiotherapy developed RN during follow-up. Surgical resection for the cerebral RN was performed in nine patients, and the other three patients received medical treatment. The clinical features, magnetic resonance imaging (MRI), surgical findings, and pathological sections are reviewed. The diagnosis of RN was confirmed by histological study in all the patients; those with surgical and medical treatment recovered. As a major complication of radiotherapy, from the clinical and neuroradiological points of view, RN may simulate tumor recurrence. Due to the increasing number of patients with RN who will need to be treated in future years, the definite diagnosis and appropriate treatment of RN remain critical. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 10% |
Student > Bachelor | 2 | 10% |
Student > Doctoral Student | 2 | 10% |
Lecturer | 1 | 5% |
Other | 1 | 5% |
Other | 4 | 20% |
Unknown | 8 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 55% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Unknown | 8 | 40% |