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Mendeley readers
| Chapter title |
Tyrosinemia and Liver Transplantation: Experience at CHU Sainte-Justine
|
|---|---|
| Chapter number | 5 |
| Book title |
Hereditary Tyrosinemia
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-3-319-55780-9_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-955779-3, 978-3-31-955780-9
|
| Authors |
Fernando Alvarez, Grant A. Mitchell |
| Abstract |
Tyrosinemia is a disease of the tyrosine metabolism, affecting mainly liver, kidney and peripheral nerves. Two forms of liver disease caused by a deficiency of FAH are recognised: (1) acute liver failure; (2) chronic liver disease. Since the introduction of NTBC [2-(2-nitro-4-trifluoromethyl benzoyl)-1-3-cyclohexanedione] (nitisinone(R)) in the treatment of tyrosinemia, no liver disease has been observed when started in the first weeks of life. Liver transplantation is a good option for the treatment of tyrosinemic patients developing liver nodules, with high suspicion of hepatocarcinoma. In the long-term outcome of the liver transplant, survival was of 90% in tyrosinemic patients. |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 27% |
| Student > Master | 2 | 18% |
| Student > Bachelor | 1 | 9% |
| Researcher | 1 | 9% |
| Student > Postgraduate | 1 | 9% |
| Other | 0 | 0% |
| Unknown | 3 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 36% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 9% |
| Veterinary Science and Veterinary Medicine | 1 | 9% |
| Nursing and Health Professions | 1 | 9% |
| Biochemistry, Genetics and Molecular Biology | 1 | 9% |
| Other | 0 | 0% |
| Unknown | 3 | 27% |