You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Chapter title |
The Tetracycline Responsive System
|
---|---|
Chapter number | 12 |
Book title |
Mammalian Synthetic Promoters
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7223-4_12 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7221-0, 978-1-4939-7223-4
|
Authors |
Nasim Yousaf, David Gould |
Abstract |
Constitutive gene expression is not always the appropriate expression system because the unphysiological levels of expressed protein could be detrimental in studies examining biological roles of proteins, or continued expression may be unnecessary after therapeutic effects have been achieved in gene therapy . We have utilized pharmacologically regulated gene expression systems to achieve fine control of gene expression levels which facilitate research in basic biology and translates to use in experimental gene therapy studies. In this chapter, we outline the application of a tightly controlled tetracycline responsive gene expression system. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 44% |
Unspecified | 1 | 11% |
Student > Master | 1 | 11% |
Unknown | 3 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 33% |
Agricultural and Biological Sciences | 2 | 22% |
Unspecified | 1 | 11% |
Medicine and Dentistry | 1 | 11% |
Unknown | 2 | 22% |