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Chapter title |
Traction Force Measurement Using Deformable Microposts
|
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Chapter number | 16 |
Book title |
Fibrosis
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Published in |
Methods in molecular biology, January 2017
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DOI | 10.1007/978-1-4939-7113-8_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7112-1, 978-1-4939-7113-8
|
Authors |
Tianfa Xie, Jamar Hawkins, Yubing Sun |
Abstract |
Recent findings suggest that mechanical forces strongly influence wound repair and fibrosis across multiple organ systems. Traction force is vital to the characterization of cellular responses to mechanical stimuli. Using hydrogel-based traction force microscopy, a FRET-based tension sensor, or microengineered cantilevers, the magnitude of traction forces can be measured. Here, we describe a traction force measurement methodology using a dense array of elastomeric microposts. This platform can be used to measure the traction force of a single cell or a colony of cells with or without geometric confinement. |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 50% |
Student > Bachelor | 1 | 17% |
Researcher | 1 | 17% |
Student > Postgraduate | 1 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 2 | 33% |
Biochemistry, Genetics and Molecular Biology | 1 | 17% |
Medicine and Dentistry | 1 | 17% |
Materials Science | 1 | 17% |
Engineering | 1 | 17% |
Other | 0 | 0% |