Chapter title |
Association of Nutrients with Biomarkers of Alzheimer’s Disease
|
---|---|
Chapter number | 23 |
Book title |
GeNeDis 2016
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-3-319-57379-3_23 |
Pubmed ID | |
Book ISBNs |
978-3-31-957378-6, 978-3-31-957379-3
|
Authors |
Efstathia G. Kalli |
Abstract |
Prospective cohort studies, cross-sectional surveys, autopsy studies and intervention clinical trials that investigated the association between nutrients and Alzheimer's disease (AD) have been reviewed. To estimate the relationship between specific nutrient intake and the risk of AD, Cochrane Library, PubMed, EMBASE, and the Fisher Center for Alzheimer's Research Foundation were searched for this purpose. Most published observational studies found an inverse relationship between vitamins, n-3 fatty acids and AD. The majority of intervention studies support the beneficial effect of combined vitamins and n-3 fatty acids providing them in the early stages of the disease. Only vitamin E and Zn supplementation failed to show any significant difference on the study population. On the other hand, high dietary intake of saturated fat and brain metal accumulation were positively associated with the incidence of AD. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 47 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 11% |
Student > Ph. D. Student | 5 | 11% |
Researcher | 4 | 9% |
Student > Master | 4 | 9% |
Student > Doctoral Student | 3 | 6% |
Other | 9 | 19% |
Unknown | 17 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 6 | 13% |
Neuroscience | 5 | 11% |
Medicine and Dentistry | 5 | 11% |
Agricultural and Biological Sciences | 3 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 4 | 9% |
Unknown | 22 | 47% |