| Chapter title |
Miscellaneous Drugs and Male Reproduction
|
|---|---|
| Chapter number | 13 |
| Book title |
Impacts of Medications on Male Fertility
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-3-319-69535-8_13 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-969534-1, 978-3-31-969535-8
|
| Authors |
Erma Z. Drobnis, Ajay K. Nangia |
| Abstract |
In addition to main categories of medications believed to have negative impacts on male reproduction, there are a number of miscellaneous drugs with some evidence for such adverse reactions. Because of its widespread use and over-the-counter availability, the H2 receptor antagonist cimetidine is most concerning. As a competitive antagonist at androgen receptors, it can impact the HPG axis and semen quality. In this chapter, we review the studies of this drug and other histamine H2 receptor antagonists in men and experimental species. Several other medications are concerning and the evidence for negative effects on reproduction are covered: colchicine, domperidone, hydroxyurea, metformin, metoclopramide, mifepristone, retinoids, and statins. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 2 | 18% |
| Professor | 2 | 18% |
| Lecturer | 1 | 9% |
| Student > Ph. D. Student | 1 | 9% |
| Student > Master | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 3 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 36% |
| Chemical Engineering | 1 | 9% |
| Agricultural and Biological Sciences | 1 | 9% |
| Nursing and Health Professions | 1 | 9% |
| Unknown | 4 | 36% |