Chapter title |
Predicting Gene Expression Noise from Gene Expression Variations
|
---|---|
Chapter number | 13 |
Book title |
Transcriptome Data Analysis
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7710-9_13 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7709-3, 978-1-4939-7710-9
|
Authors |
Xiaojian Shao, Ming-an Sun, Shao, Xiaojian, Sun, Ming-an |
Abstract |
The level of gene expression is known to vary from cell to cell and even in the same cell over time. This variability provides cells with the ability to mitigate environmental stresses and genetic perturbations, and facilitates gene expression evolution. Recently, many valuable gene expression noise data measured at the single-cell level and gene expression variation measured for cell populations have become available. In this chapter, we show how to perform integrative analysis using these data. Specifically, we introduce how to apply a machine learning technique (support vector regression) to explore the relationship between gene expression variations and stochastic noise. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 30% |
Student > Bachelor | 2 | 20% |
Unspecified | 1 | 10% |
Researcher | 1 | 10% |
Student > Master | 1 | 10% |
Other | 0 | 0% |
Unknown | 2 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 30% |
Agricultural and Biological Sciences | 2 | 20% |
Computer Science | 1 | 10% |
Unspecified | 1 | 10% |
Unknown | 3 | 30% |