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Retinal Degeneration

Overview of attention for book
Cover of 'Retinal Degeneration'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Identification and analysis of inherited retinal disease genes.
  3. Altmetric Badge
    Chapter 2 Mouse Models for Studies of Retinal Degeneration and Diseases
  4. Altmetric Badge
    Chapter 3 Retinal Fundus Imaging in Mouse Models of Retinal Diseases
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    Chapter 4 Functional Phenotyping of Mouse Models with ERG
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    Chapter 5 Phenotyping of Mouse Models with OCT
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    Chapter 6 Light Damage as a Model of Retinal Degeneration
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    Chapter 7 N -Methyl- d -Aspartate (NMDA)-Mediated Excitotoxic Damage: A Mouse Model of Acute Retinal Ganglion Cell Damage
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    Chapter 8 Generation of Transgenic X. laevis Models of Retinal Degeneration
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    Chapter 9 Analysis of Photoreceptor Degeneration in the Zebrafish Danio rerio
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    Chapter 10 Analysis of Optokinetic Response in Zebrafish by Computer-Based Eye Tracking
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    Chapter 11 Analysis of the Drosophila Compound Eye with Light and Electron Microscopy
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    Chapter 12 Cell-Specific Markers for the Identification of Retinal Cells by Immunofluorescence Microscopy
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    Chapter 13 A Method of Horizontally Sliced Preparation of the Retina
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    Chapter 14 Detection of DNA Fragmentation in Retinal Apoptosis by TUNEL
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    Chapter 15 High-Throughput RNA In Situ Hybridization in Mouse Retina
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    Chapter 16 Assessment of Mitochondrial Damage in Retinal Cells and Tissues Using Quantitative Polymerase Chain Reaction for Mitochondrial DNA Damage and Extracellular Flux Assay for Mitochondrial Respiration Activity
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    Chapter 17 Analysis of Photoreceptor Rod Outer Segment Phagocytosis by RPE Cells In Situ
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    Chapter 18 Ca 2+ Microfluorimetry in Retinal Müller Glial Cells
  20. Altmetric Badge
    Chapter 19 Functional Analysis of Retinal Microglia and Their Effects on Progenitors
  21. Altmetric Badge
    Chapter 20 Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture
  22. Altmetric Badge
    Chapter 21 Ca 2+ -Imaging Techniques to Analyze Ca 2+ Signaling in Cells and to Monitor Neuronal Activity in the Retina
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    Chapter 22 Double Chromatin Immunoprecipitation: Analysis of Target Co-occupancy of Retinal Transcription Factors
  24. Altmetric Badge
    Chapter 23 Quantifying the Activity of cis -Regulatory Elements in the Mouse Retina by Explant Electroporation
  25. Altmetric Badge
    Chapter 24 Optimized Technique for Subretinal Injections in Mice
  26. Altmetric Badge
    Chapter 25 Adeno-associated viral vectors for gene therapy of inherited retinal degenerations.
  27. Altmetric Badge
    Chapter 26 Barrier Modulation in Drug Delivery to the Retina
Attention for Chapter 1: Identification and analysis of inherited retinal disease genes.
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Chapter title
Identification and analysis of inherited retinal disease genes.
Chapter number 1
Book title
Retinal Degeneration
Published in
Methods in molecular biology, November 2012
DOI 10.1007/978-1-62703-080-9_1
Pubmed ID
Book ISBNs
978-1-62703-079-3, 978-1-62703-080-9
Authors

Neveling K, den Hollander AI, Cremers FP, Collin RW, Kornelia Neveling, Anneke I. den Hollander, Frans P. M. Cremers, Rob W. J. Collin

Abstract

Inherited retinal diseases display a very high degree of clinical and genetic heterogeneity, which poses challenges in identifying the underlying defects in known genes and in identifying novel retinal disease genes. Here, we outline the state-of-the-art techniques to find the causative DNA variants, with special attention for next-generation sequencing which can combine molecular diagnostics and retinal disease gene identification.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 27%
Researcher 3 27%
Student > Master 2 18%
Other 1 9%
Student > Bachelor 1 9%
Other 1 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 45%
Agricultural and Biological Sciences 4 36%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Medicine and Dentistry 1 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2013.
All research outputs
#3,349,187
of 4,723,001 outputs
Outputs from Methods in molecular biology
#1,665
of 3,448 outputs
Outputs of similar age
#61,111
of 90,589 outputs
Outputs of similar age from Methods in molecular biology
#12
of 20 outputs
Altmetric has tracked 4,723,001 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,448 research outputs from this source. They receive a mean Attention Score of 1.4. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,589 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.