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Chemical Biology

Overview of attention for book
Cover of 'Chemical Biology'

Table of Contents

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    Book Overview
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    Chapter 1 Identification of therapeutic small-molecule leads in cultured cells using multiplexed pathway reporter readouts.
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    Chapter 2 Applying the logic of genetic interaction to discover small molecules that functionally interact with human disease alleles.
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    Chapter 3 Construction and application of a photo-cross-linked chemical array.
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    Chapter 4 High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells.
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    Chapter 5 Small-Molecule High-Throughput Screening Utilizing Xenopus Egg Extract.
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    Chapter 6 Fission Yeast-Based High-Throughput Screens for PKA Pathway Inhibitors and Activators.
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    Chapter 7 A Method for High-Throughput Analysis of Chronological Aging in Schizosaccharomyces pombe.
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    Chapter 8 Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis
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    Chapter 9 Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium
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    Chapter 10 Small-Molecule Screening Using Drosophila Models of Human Neurological Disorders.
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    Chapter 11 High-Throughput Small-Molecule Screening in Caenorhabditis elegans.
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    Chapter 12 Whole-Organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish
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    Chapter 13 High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish
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    Chapter 14 Extraction Methods of Natural Products from Traditional Chinese Medicines
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    Chapter 15 Bioassay-Guided Identification of Bioactive Molecules from Traditional Chinese Medicines
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    Chapter 16 NMR screening in fragment-based drug design: a practical guide.
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    Chapter 17 Practical Strategies for Small-Molecule Probe Development in Chemical Biology
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    Chapter 18 Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.
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    Chapter 19 Small-Molecule Library Screening by Docking with PyRx.
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    Chapter 20 Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions
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    Chapter 21 Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics.
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    Chapter 22 Drug Affinity Responsive Target Stability (DARTS) for Small-Molecule Target Identification.
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    Chapter 23 Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action.
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    Chapter 24 Image-Based Prediction of Drug Target in Yeast.
Attention for Chapter 18: Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.
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Citations

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Chapter title
Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.
Chapter number 18
Book title
Chemical Biology
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2269-7_18
Pubmed ID
25618349
Book ISBNs
978-1-4939-2268-0, 978-1-4939-2269-7
Authors

Wenderski TA, Stratton CF, Bauer RA, Kopp F, Tan DS, Todd A. Wenderski, Christopher F. Stratton, Renato A. Bauer, Felix Kopp, Derek S. Tan

View on publisher site
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 18%
Student > Ph. D. Student 8 15%
Student > Bachelor 6 11%
Student > Postgraduate 5 9%
Student > Master 5 9%
Other 9 16%
Unknown 12 22%
Readers by discipline Count As %
Chemistry 24 44%
Biochemistry, Genetics and Molecular Biology 7 13%
Agricultural and Biological Sciences 2 4%
Engineering 2 4%
Physics and Astronomy 1 2%
Other 2 4%
Unknown 17 31%

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