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Human Embryonic Stem Cells Handbook

Overview of attention for book
Cover of 'Human Embryonic Stem Cells Handbook'

Table of Contents

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    Book Overview
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    Chapter 1 Establishment of New Lines of Human Embryonic Stem Cells: Evolution of the Methodology
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    Chapter 2 Human Embryonic Stem Cells Derived in Xeno-Free Conditions
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    Chapter 3 Procedures for Derivation and Characterisation of Human Embryonic Stem Cells from Odense, Denmark
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    Chapter 4 Principles for Derivation of Human Embryonic Stem Cells
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    Chapter 5 Derivation and Maintenance of Undifferentiated Human Embryonic Stem Cells
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    Chapter 6 Establishment of hESC Lines from the Inner Cell Mass of Blastocyst-Stage Embryos and Single Blastomeres of 4-Cell Stage Embryos
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    Chapter 7 Analysis of LINE-1 Expression in Human Pluripotent Cells.
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    Chapter 8 Characterization and Gene Expression Profiling of Five Human Embryonic Stem Cell Lines Derived in Taiwan
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    Chapter 9 Derivation of Human Embryonic Stem Cell Lines from Poor Quality Embryos
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    Chapter 10 Derivation, Expansion, and Characterization of Human Embryonic Stem Cell Lines from Aneuploid Embryos
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    Chapter 11 Mutated human embryonic stem cells for the study of human genetic disorders.
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    Chapter 12 Single-Cell Enzymatic Dissociation of hESC Lines OxF1–OxF4 and Culture in Feeder-Free Conditions
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    Chapter 13 Protocol for Expansion of Undifferentiated Human Embryonic and Pluripotent Stem Cells in Suspension
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    Chapter 14 Suspension Bioreactor Expansion of Undifferentiated Human Embryonic Stem Cells
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    Chapter 15 Derivation, Propagation, and Characterization of Neuroprogenitors from Pluripotent Stem Cells (hESCs and hiPSCs)
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    Chapter 16 Comparison of Neural Differentiation Potential of Human Pluripotent Stem Cell Lines Using a Quantitative Neural Differentiation Protocol
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    Chapter 17 Array-Comparative Genomic Hybridization Characterization of Human Pluripotent Stem Cells
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    Chapter 18 Chromatin Immunoprecipitation-Based Analysis of Gene Regulatory Networks Operative in Human Embryonic Stem Cells
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    Chapter 19 Analysis of the Methylome of Human Embryonic Stem Cells Employing Methylated DNA Immunoprecipitation Coupled to Next-Generation Sequencing
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    Chapter 20 Stable Isotope Labelling with Amino Acids in Cell Culture for Human Embryonic Stem Cell Proteomic Analysis
Attention for Chapter 11: Mutated human embryonic stem cells for the study of human genetic disorders.
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Chapter title
Mutated human embryonic stem cells for the study of human genetic disorders.
Chapter number 11
Book title
Human Embryonic Stem Cells Handbook
Published in
Methods in molecular biology, January 2012
DOI 10.1007/978-1-61779-794-1_11
Pubmed ID
22528355
Book ISBNs
978-1-61779-793-4, 978-1-61779-794-1
Authors

Ahmi Ben-Yehudah, Mira Malcov, Tsvia Frumkin, Dalit Ben-Yosef

Abstract

Human embryonic stem cells (HESCs) are of great interest in biology and medicine due to their ability to grow indefinitely in culture while maintaining their ability to differentiate into all different cell types in the human body. In addition, HESCs can be used for better understanding the key developmental processes and can, therefore, serve for studying genetic disorders for which no good research model exists. Preimplantation genetic diagnosis of in vitro derived embryos results in affected-spare blastocysts with specific known inherited mutations.These affected blastocysts can be used for the derivation of disease-bearing HESCs, which would serve for studying the molecular and pathophysiological mechanisms underlying the genetic disease for which they were diagnosed. This chapter describes the methods to derive HESCs carrying mutations for inherited disorders.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Researcher 1 11%
Student > Doctoral Student 1 11%
Student > Master 1 11%
Unknown 3 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 1 11%
Neuroscience 1 11%
Medicine and Dentistry 1 11%
Unknown 4 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2012.
All research outputs
#18,305,773
of 22,664,644 outputs
Outputs from Methods in molecular biology
#7,815
of 13,025 outputs
Outputs of similar age
#195,924
of 244,053 outputs
Outputs of similar age from Methods in molecular biology
#325
of 473 outputs
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So far Altmetric has tracked 13,025 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 473 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.

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