Chapter title |
Hypersensitivity reactions to food colours with special reference to the natural colour annatto extract (butter colour).
|
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Chapter number | 16 |
Book title |
Toxicological Aspects of Food Safety
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Published in |
Archives of toxicology Supplement Archiv für Toxikologie Supplement, January 1978
|
DOI | 10.1007/978-3-642-66896-8_16 |
Pubmed ID | |
Book ISBNs |
978-3-54-008646-8, 978-3-64-266896-8
|
Authors |
H Mikkelsen, J C Larsen, F Tarding, Mikkelsen, H, Larsen, J C, Tarding, F, H. Mikkelsen, J. C. Larsen, F. Tarding, Mikkelsen, H., Larsen, J. C., Tarding, F. |
Abstract |
It is well known that synthetic food colours especially some azo dyes can provoke hypersensitivity reactions such as urticaria, angioneurotic oedema, and astma (Michaëlsson and Juhlin, 1973, Granholt and Thune, 1975). Natural food colours are scarcely investigated with respect to potential allergic properties. Annatto extract, a commonly used food colour in edible fats e.g. butter, has been tested in patients. Among 61 consecutive patients suffereing from chornic urticaria and/or angioneurotic oedema 56 patients were orally provoked by annatto extract during elimination diet. Challenge was performed with a dose equivalent to the amount used in 25 grammes of butter. Twentysix per cent of the patients reacted to this colour 4 hours (SD: 2,6) after intake. Similar challenges with synthetic dyes showed the following results: Tartrazine 11%, Sunset Yellow FCF 17%, Food Red 17 16%, Amaranth 9%, Ponceau 4 R 15%, Erythrosine 12% and Brillant Blue FCF 14%. The present study indicates that natural food colours may induce hypersensitivity reactions as frequent as synthetic dyes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 19% |
Student > Doctoral Student | 3 | 12% |
Student > Bachelor | 3 | 12% |
Student > Ph. D. Student | 2 | 8% |
Student > Master | 2 | 8% |
Other | 2 | 8% |
Unknown | 9 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 31% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Chemistry | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Other | 2 | 8% |
Unknown | 9 | 35% |