Chapter title |
Dendritic cells as immunogens for human CTL responses.
|
---|---|
Chapter number | 62 |
Book title |
Dendritic Cells in Fundamental and Clinical Immunology
|
Published in |
Advances in experimental medicine and biology, January 1997
|
DOI | 10.1007/978-1-4757-9966-8_62 |
Pubmed ID | |
Book ISBNs |
978-1-4757-9968-2, 978-1-4757-9966-8
|
Authors |
Bender, A, Sapp, M, Feldman, M, Reddy, A, Seder, R, Schuler, G, Steinman, R M, Bhardwaj, N, Armin Bender, Mark Sapp, Mary Feldman, Anita Reddy, Robert Seder, Gerold Schuler, Ralph M. Steinman, Nina Bhardwaj, Bender, Armin, Sapp, Mark, Feldman, Mary, Reddy, Anita, Seder, Robert, Schuler, Gerold, Steinman, Ralph M., Bhardwaj, Nina |
Abstract |
The cellular requirements for generating potent human CD8+ CTLs to influenza A virus in vitro have been defined. Furthermore, we have developed improved methods for generating large numbers of DCs from non-proliferating progenitors. These developments have enabled the design of new strategies to elicit CTLs in vivo. For example, together with IL-12, antigen-pulsed DCs may be a useful approach for boosting CTL responses against infectious agents and malignancies. Our results also reopen the potential use of inactivated virus preparations as immunogens for CTL responses. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 7% |
Unknown | 14 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 47% |
Professor | 4 | 27% |
Professor > Associate Professor | 2 | 13% |
Student > Master | 1 | 7% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 40% |
Agricultural and Biological Sciences | 3 | 20% |
Immunology and Microbiology | 3 | 20% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Unknown | 2 | 13% |