We validated ~40% of previously reported whole blood #dnamethylation #biomarkers of sex using ~6k independent whole blood and PBMC samples. Validated maker effect size and direction were highly correlated and concordant across analyses https://t.co/Y3FU7hE
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RT @BiologySexDiff: This 2015 study investigated sex-biased #DNAmethylation on the autosomes in blood by adjusting for estimated cellular p…
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This 2015 study investigated sex-biased #DNAmethylation on the autosomes in blood by adjusting for estimated cellular proportions, as cell-type proportions may vary by sex. DNA methylation plays an key role in both normal & disease development: https:/