| Chapter title |
Magnesium Homeostasis in Mammalian Cells
|
|---|---|
| Chapter number | 4 |
| Book title |
Metallomics and the Cell
|
| Published in |
Metal ions in life sciences, December 2012
|
| DOI | 10.1007/978-94-007-5561-1_4 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-075560-4, 978-9-40-075561-1
|
| Authors |
Andrea M. P. Romani, Romani, Andrea M. P. |
| Editors |
Lucia Banci |
| Abstract |
Magnesium, the second most abundant cation within the cell, plays an important role in numerous biological functions. Experimental evidence indicates that mammalian cells tightly regulate cellular magnesium ion content through specific mechanisms controlling Mg(2+) entry and efflux across the cell membrane and the membrane of various cellular organelles as well as intracellular Mg(2+) buffering under resting conditions and following hormonal and metabolic stimuli. This chapter will provide an assessment of the various mechanisms controlling cellular Mg(2+) homeostasis and transport, and the implications changes in cellular Mg(2+) content play under physiological and pathological conditions. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 41 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 24% |
| Researcher | 9 | 21% |
| Student > Master | 6 | 14% |
| Student > Bachelor | 4 | 10% |
| Student > Doctoral Student | 3 | 7% |
| Other | 3 | 7% |
| Unknown | 7 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 15 | 36% |
| Biochemistry, Genetics and Molecular Biology | 6 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 10% |
| Medicine and Dentistry | 4 | 10% |
| Chemistry | 4 | 10% |
| Other | 3 | 7% |
| Unknown | 6 | 14% |