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Systematic neonatal screening for congenital Chagas disease in Northeast Brazil: prevalence of Trypanosoma cruzi infection in the Southern region of Sergipe

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, June 2018
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Title
Systematic neonatal screening for congenital Chagas disease in Northeast Brazil: prevalence of Trypanosoma cruzi infection in the Southern region of Sergipe
Published in
Revista da Sociedade Brasileira de Medicina Tropical, June 2018
DOI 10.1590/0037-8682-0024-2018
Pubmed ID
Authors

Fábia Regina dos Santos, Diana Matos Euzébio, Genilde Gomes de Oliveira, Mayra Souza Chagas, Alex Ricardo Ferreira, Lídia Almeida Mendonça, Dalmo Correia, Angela Maria da Silva

Abstract

Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi, being one of the leading causes of morbidity and mortality in the Americas with an estimated six to seven million infected people worldwide. In Brazil, the improvement in vector control and blood donor screening has evidenced the important epidemiological role of congenital transmission of Chagas disease. A serological survey for Chagas disease was performed in 3,952 newborns in the southern region of Sergipe using paper filter disks of dried blood samples. The newborns were screened using the Sergipe State Neonatal Screening Program between July 2015 and July 2016, and 3,749 and 750 blood samples were obtained for the IgG enzyme-linked immunosorbent assay and indirect immunofluorescence assay, respectively. In addition, mothers of the children who presented initial reagent serology were examined. Among 3,749 blood samples, samples of two children were positive for the enzyme-linked immunosorbent assay; however, their confirmation test results were negative, suggesting passive transfer of the mother's antibody. One puerpera was identified with Chagas disease, with a prevalence of 0.02%. Congenital Chagas disease was not observed in newborns in the Southern region of Sergipe. However, Chagas disease was observed in women of reproductive age. Therefore, effective measurements for monitoring and systematic evaluation should be conducted. The Neonatal Screening Program proved to be an effective public health strategy for the prevention and control of Chagas disease.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 13%
Student > Master 5 13%
Student > Postgraduate 3 8%
Student > Doctoral Student 3 8%
Researcher 3 8%
Other 8 21%
Unknown 12 31%
Readers by discipline Count As %
Medicine and Dentistry 4 10%
Biochemistry, Genetics and Molecular Biology 3 8%
Engineering 3 8%
Agricultural and Biological Sciences 3 8%
Nursing and Health Professions 2 5%
Other 7 18%
Unknown 17 44%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2018.
All research outputs
#10,504,642
of 13,184,150 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#93
of 194 outputs
Outputs of similar age
#199,754
of 267,449 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#1
of 1 outputs
Altmetric has tracked 13,184,150 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 194 research outputs from this source. They receive a mean Attention Score of 1.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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