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Candida Species

Overview of attention for book
Cover of 'Candida Species'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Candida Species
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    Chapter 2 Candida Species
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    Chapter 3 SRYTH: A New Yeast Two-Hybrid Method.
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    Chapter 4 Chromatin Immunoprecipitation (ChIP) Assay in Candida albicans.
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    Chapter 5 Candida Species
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    Chapter 6 Candida Species
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    Chapter 7 Identification of Secreted Candida Proteins Using Mass Spectrometry.
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    Chapter 8 In Vitro Models for Candida Biofilm Development.
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    Chapter 9 The Fungal Biome of the Oral Cavity.
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    Chapter 10 Experimental Models of C. albicans-Streptococcal Co-infection.
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    Chapter 11 Staphylococcus-Candida Interaction Models: Antibiotic Resistance Testing and Host Interactions.
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    Chapter 12 Genetic Screens for Determination of Mechanism of Action.
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    Chapter 13 Candida Species
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    Chapter 14 Biofilms and Antifungal Susceptibility Testing.
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    Chapter 15 Candida Species
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    Chapter 16 Candida Species
Attention for Chapter 12: Genetic Screens for Determination of Mechanism of Action.
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Chapter title
Genetic Screens for Determination of Mechanism of Action.
Chapter number 12
Book title
Candida Species
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3052-4_12
Pubmed ID
26519072
Book ISBNs
978-1-4939-3051-7, 978-1-4939-3052-4
Authors

Gay-Andrieu, Françoise, Alex, Deepu, Calderone, Richard, Françoise Gay-Andrieu, Deepu Alex, Richard Calderone

Abstract

The search for new antifungal drugs and cell targets continues. During the discovery process, mechanism-of-action (MOA) studies are critical to the continued progress of the compound through the pipeline. There are many approaches that can be utilized in understanding the MOA. One of these approaches is a genetic screen utilizing the availability of Saccharomyces cerevisiae mutant libraries. Both null and heterozygous library mutants covering the entire genome of this model yeast are available. The desired phenotype when screening the new compound is either resistance (null mutants) or haploinsufficiency or loss of fitness (heterozygote mutants). Both types of mutants can be clustered by software into common targets that provide clues as to a pathway or other cell process. Below, methods are described for genetic screens.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 22%
Other 1 11%
Student > Master 1 11%
Student > Bachelor 1 11%
Professor > Associate Professor 1 11%
Other 1 11%
Unknown 2 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 22%
Medicine and Dentistry 2 22%
Chemistry 1 11%
Agricultural and Biological Sciences 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2016.
All research outputs
#18,429,829
of 22,831,537 outputs
Outputs from Methods in molecular biology
#7,920
of 13,126 outputs
Outputs of similar age
#284,422
of 393,555 outputs
Outputs of similar age from Methods in molecular biology
#846
of 1,470 outputs
Altmetric has tracked 22,831,537 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,126 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.

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