Jan van Deursen’s senolytics: from bench to failed clinical trial
For Better Science,
Jan van Deursen had to resign from Mayo Clinic over bullying charges. With his company Unity Biotech's phase 2 clinical trial…
Unity Biotechnology and Senescent Cell Therapy
In the Pipeline,
Let’s have a look at the case of Unity Biotechnology, because this is a story that won’t get so many headlines. Unity has been…
Un medicamento para el corazón logra rejuvenecer a animales en laboratorio
EcoAvant.com - Portada,
La vida, en el límite, parece llevar el apellido Hayflick. En 1961, este investigador contempló atónito en su laboratorio cómo…
The Potential of Senolytic Therapies to Treat Chronic Kidney Disease
Fight Aging!,
Senescent cells are a cause of aging. While near all senescent cells are destroyed shortly after entering that state, either by…
Senolytics: Antibiotics Identified As Potential Anti-aging Drugs
ReliaWire,
An FDA-approved antibiotic – Azithromycin – can effectively target and eliminate senescent cells in culture, according to the…
Longevity FAQ
Marginal Revolution,
From Laura Deming, you will find it here, essential reading for our time. Here is one bit…
Flushing out 'zombie cells' could help stave off Parkinson's, study suggests
Science news, comment and analysis | theguardian.com,
Possible approach to treating effects of neurodegenerative diseases – and even ageing – revealed by trialIn work that could…
Living forever: Can we reverse the biology of ageing?
Forum:Blog,
Lindsay Wu explores the research currently being done into extending the human lifespan and reversing biological ageing.
Senolytics against Aging: Snapshot of a Fast-Moving Field
Josh Mitteldorf,
Aging at the cellular level is called “cell senescence”, and it contributes profoundly to whole-body aging. The most promising…
Senolytics against Aging: Snapshot of a Fast-Moving Field
Josh Mitteldorf,
Aging at the cellular level is called “cell senescence”, and it contributes profoundly to whole-body aging. The most promising…
Killing 'zombie' cells to improve health in old age
Ageing Research,
Dominick Burton, Research Fellow, Aston UniversityThis article was originally published on The Conversation. Read the original…
Happy New Year: Looking Back at 2016 Research Highlights
NIH Director's Blog,
Happy New Year! While everyone was busy getting ready for the holidays, the journal Science announced its annual compendium of…
Killing old cells to stay young.
Deric Bownds' MindBlog,
I want to pass on one of Science Magazine's choices for the top ten scientific breakthroughs of the year. Pricey plastic…
Combattere l’invecchiamento distruggendo le cellule vecchie: una delle scoperte dell’anno secondo Science
OggiScienza,
ATTUALITÀ – Complici un calo delle nascite che non dà cenno di fermarsi e un allungamento dell’aspettativa di vita, la…
Anti-Aging Startup Raises $116 Million With big VCs and Amazon CEO Jeff Bezos Backing
Next Big Future,
Unity Biotechnology said Thursday that it attracted support for the Series B funding round from traditional biotech investors…
The race to develop senescent cell clearance therapies
Signals Blog,
Confocal microscopy photographs of the descending aortas of two 15-month-old progeria mice, one untreated (left) and the other…
How Animal Testing and Research is Advancing Treatments for Type 2 Diabetes
Foundation for Biomedical Research,
This is the second installment of a 3-part series covering some of the contributions animals have made to treatments for…
How Animal Testing and Research is Advancing Treatments for Type 2 Diabetes
Foundation for Biomedical Research,
This is the second installment of a 3-part series covering some of the contributions animals have made to treatments for…
Getting rid of old cells extends lifespan of mice and ameliorates age-related diseases.
Deric Bownds' MindBlog,
Baker et al. show that getting rid of cells that have entered an irreversible senescent state expands the lifespan of mice and…
A Little Backstory for UNITY Biotechnology
Fight Aging!,
UNITY Biotechnology made a big splash a few weeks ago to announce their venture funding and intent to develop a senescent cell…
Senescent cells tied to health and longevity in mice
NIH Research Matters,
Removing senescent cells — those that had stopped dividing — extended the lifespan of mice and had other health benefits…
Nature：衰老细胞的有害影响
生物360最新文章,
各种组织和器官在正常老化过程中积累衰老细胞，但不知道这些细胞是否
The Secret To Staying Young? Scientists Boost Lifespan Of Mice By Deleting Defective Cells
IFLScience - Health and Medicine,
Health and…
What if we could slow ageing by deleting defective cells?
Forum:Blog,
The ageing population is one of the greatest challenges facing society. More people are surviving to old age than ever before…
‘one of the most important aging discoveries ever’
Josh Mitteldorf,
The science news circuits have been buzzing about Jan van Deursen’s recent paper, in which mice stayed younger, longer when…
Cells Weekly – February 7, 2016
Stem Cell Assays,
Cells Weekly is a digest of the most interesting news and events in stem cell research, cell therapy and regenerative medicine.
The Philosopher’s Stone?
Pharmaceutical Intelligence,
The Philosopher’s Stone? Larry H. Bernstein, MD, FCAP, Curator LPBI Mitochondria trigger cell aging, researchers discover How…
SciNat за февраль 2016 #1: клещи-переносчики вирусов пчел, клетки старения, белки от облысения и болезней сердца
"Биомолекула",
На этой неделе произошло важное событие: в
En les débarrassant de leurs cellules HS des souris ont vécue 25 % plus longtemps et en bonne santé
GuruMeditation,
Guru…
Mice Lived Substantially Longer When Type of Cell Removed
Science | KQED Public Media for Northern CA,
Mice were much healthier and lived about 25 percent longer when scientists killed off a certain kind of cell that accumulates…
Want To Live Longer? Clearing Out Old 'Zombie' Cells Might Extend Life Up To 35 Percent
Medical Daily,
Senescent cells are sitting around your body, and they're up to no good.
New Technique Extends Lifespan Of Mice By Up To 35 Percent
IFLScience - Health and Medicine,
Health and…
Scientists extend life of mice by 35 per cent by removing accumulated cells that no longer divide with compound AP20187
Next Big Future,
Researchers at Mayo Clinic have shown that senescent cells – cells that no longer divide and accumulate with age – negatively…
Killing off Senescent Cells Extends the Life and Improves the Health of Laboratory Mice
Beyond the Dish,
Our bodies contain a mixture of cells that grow and others whose growing days are long since over. Such cells are called “senesce…
Removing Worn-Out Cells Increases Lifespan
Counsel & Heal : Top News,
By removing worn-out cells in mice, scientists were able to increase lifespan, kidney functioning and the heart's health.
Clearing out damaged cells in mice extends lifespan by up to 35 percent
Gizmag Emerging Technology Magazine,
As we age, cells within our bodies can become damaged. As a way of helping prevent cancers developing, a biological mechanism…
Boosting Life Span By Clearing Out Cellular Clutter
Shots - Health News,
Listen to the Story All Things Considered
Boosting Life Span By Clearing Out Cellular Clutter
Health,
So-called senescent cells no longer divide, but they secrete a mixture of chemicals that can trigger inflammation, which is…
25% Median Life Extension in Mice via Senescent Cell Clearance, Unity Biotechnology Founded to Develop Therapies
Fight Aging!,
With today's news, it certainly seems that senescent cell clearance has come of age as an approach to treating aging and age-rela…
Mayo Clinic researchers extend lifespan by up to 35 percent in mice
KurzweilAI,
Aged mice with and without senescent cell clearance (credit: Mayo Clinic) Researchers at Mayo Clinic have discovered that…