Jan van Deursen’s senolytics: from bench to failed clinical trial
For Better Science,
Jan van Deursen had to resign from Mayo Clinic over bullying charges. With his company Unity Biotech's phase 2 clinical trial…
Jan van Deursen had to resign from Mayo Clinic over bullying charges. With his company Unity Biotech's phase 2 clinical trial…
Let’s have a look at the case of Unity Biotechnology, because this is a story that won’t get so many headlines. Unity has been…
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Senescent cells are a cause of aging. While near all senescent cells are destroyed shortly after entering that state, either by…
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Aging at the cellular level is called “cell senescence”, and it contributes profoundly to whole-body aging. The most promising…
Aging at the cellular level is called “cell senescence”, and it contributes profoundly to whole-body aging. The most promising…
Dominick Burton, Research Fellow, Aston UniversityThis article was originally published on The Conversation. Read the original…
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Unity Biotechnology said Thursday that it attracted support for the Series B funding round from traditional biotech investors…
Confocal microscopy photographs of the descending aortas of two 15-month-old progeria mice, one untreated (left) and the other…
This is the second installment of a 3-part series covering some of the contributions animals have made to treatments for…
This is the second installment of a 3-part series covering some of the contributions animals have made to treatments for…
Baker et al. show that getting rid of cells that have entered an irreversible senescent state expands the lifespan of mice and…
UNITY Biotechnology made a big splash a few weeks ago to announce their venture funding and intent to develop a senescent cell…
Removing senescent cells — those that had stopped dividing — extended the lifespan of mice and had other health benefits…
各种组织和器官在正常老化过程中积累衰老细胞,但不知道这些细胞是否
Health and…
The ageing population is one of the greatest challenges facing society. More people are surviving to old age than ever before…
The science news circuits have been buzzing about Jan van Deursen’s recent paper, in which mice stayed younger, longer when…
Cells Weekly is a digest of the most interesting news and events in stem cell research, cell therapy and regenerative medicine.
The Philosopher’s Stone? Larry H. Bernstein, MD, FCAP, Curator LPBI Mitochondria trigger cell aging, researchers discover How…
На этой неделе произошло важное событие: в
Guru…
Mice were much healthier and lived about 25 percent longer when scientists killed off a certain kind of cell that accumulates…
Senescent cells are sitting around your body, and they're up to no good.
Health and…
Researchers at Mayo Clinic have shown that senescent cells – cells that no longer divide and accumulate with age – negatively…
Our bodies contain a mixture of cells that grow and others whose growing days are long since over. Such cells are called “senesce…
By removing worn-out cells in mice, scientists were able to increase lifespan, kidney functioning and the heart's health.
As we age, cells within our bodies can become damaged. As a way of helping prevent cancers developing, a biological mechanism…
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So-called senescent cells no longer divide, but they secrete a mixture of chemicals that can trigger inflammation, which is…
With today's news, it certainly seems that senescent cell clearance has come of age as an approach to treating aging and age-rela…
Aged mice with and without senescent cell clearance (credit: Mayo Clinic) Researchers at Mayo Clinic have discovered that…