ぼんやりとしか知らなかった「若返り研究」経緯を短時間で聴けるありがたさ!これを効率的と言わずしてなんと呼ぶのか。なんか違うけど年寄りだから許してちょ。 老化細胞(慢性炎症成れの果て細胞)を薬で取り除くよう設計し若返りマウスを作成、という2016年の報告を紹介。 https://t.co/SRUthVU2Il https://t.co/9RUkUIScMM
@ArbleMatan @orlyf6 המחקר שהרשים והלהיב אותי במקור הוא זה: https://t.co/qi8Rzsp3oq אבל כבר עברו לא מעט שנים והיו עוד ועוד עבודות שהראו דברים דומים..
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan (2016) https://t.co/iqt3thX5Yo https://t.co/zD1P50cqYg
@slavov_n @Jeff_Mold @_AndrewLeduc @RuxandraTeslo @DevoEvoMed @PLOSBiology seems relevant that the senior author of this paper suggesting lifespan extension from senescence cell clearance was fired for creating a toxic lab environment. My impression was th
RT @yasu0804: 急性ストレスや怪我の下ではSASPは有益であるが、高齢者の老化細胞の蓄積の結果として発生する持続的なSASPは慢性炎症を引き起こす 若いマウスに老化細胞を移植すると、色々な加齢関連疾患が誘発される 老化マウスから老化細胞を取り除くと臓器系が改善さ…
@JasonColasanti https://t.co/4vjTjKFGGH This is probably the most relevant study from the Mayo Clinic.
@Blagosklonny How about? (With and without progeroid models) https://t.co/3lrInTxv1S or https://t.co/BXiG3vYgio I agree that ageing is probably multifactorial, but senescence appears to play its small role in it
急性ストレスや怪我の下ではSASPは有益であるが、高齢者の老化細胞の蓄積の結果として発生する持続的なSASPは慢性炎症を引き起こす 若いマウスに老化細胞を移植すると、色々な加齢関連疾患が誘発される 老化マウスから老化細胞を取り除くと臓器系が改善され寿命が延びる https://t.co/58ItBlplO3
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan https://t.co/2dbt72fqHc https://t.co/fBa7uLtmqN
p16をターゲットにする事の有用性。fig2にある通り、平均寿命は伸びてるが最大寿命はほぼ変化がない。つまり健康寿命の延長。 つまり幹細胞の最終的な老化は抑えられない。不老不死は難しい。 Naturally occurring p16Ink4a-positive cells shorten healthy lifespan | Nature https://t.co/DQSfz3q5g6
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan | Nature https://t.co/dLHQKKLJRV
Nature: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/h6Vfs17A4z
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature : Nature Research https://t.co/4OvYNWAvta
Cellular Fountain of Youth! Clearing p16Ink4a-positive cells prolong healthy lifespan https://t.co/7x9tzLMOr6
Jan "final answer:115" Vijg: mouse senescent cell clear-out paper https://t.co/dfuV4f0Miz left maximum lifespan question open, heard of it?
RT @VIBTechWatch: Therapeutic removal of senescent cells may be an attractive approach to extend healthy lifespan; https://t.co/egNRa8oFqf…
Therapeutic removal of senescent cells may be an attractive approach to extend healthy lifespan; https://t.co/egNRa8oFqf @UnityBiotech
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/74QlodVFdn #immunesystem #GMOs #chemicals #molecules #data
RT @F1000: One bad turn deserves another: evidence that senescent cells may themselves promote aging-related pathology https://t.co/pdtNQpN…
RT @F1000: One bad turn deserves another: evidence that senescent cells may themselves promote aging-related pathology https://t.co/pdtNQpN…
One bad turn deserves another: evidence that senescent cells may themselves promote aging-related pathology https://t.co/pdtNQpNEz9
JCから:細胞老化をきたした細胞を取り除くと加齢変化が軽減して寿命が延びる。ここでは遺伝子操作によりp16INK4aを発現するとアポトーシス誘導できるように工夫。細胞老化した細胞を選択的に除去できれば、始皇帝が夢見た薬に?? https://t.co/mlbdugXCnB
Listen in how #artificial #intelligence may replace you: https://t.co/BtvZfZ33oj while reading how to live longer: https://t.co/7ytEg6YRDL
Fascinating paper on the effects of senescent cell targeting in mice https://t.co/XHFmQxOTYK
RT @GeriSciDoc: Long awaited: Reducing senescent cells extends life/health in normal mice. Prob'ly delays cancers. https://t.co/fHidTdzyQO …
Long awaited: Reducing senescent cells extends life/health in normal mice. Prob'ly delays cancers. https://t.co/fHidTdzyQO #Geroscience
"@CellSenResearch: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/EUYCxCKiLt"
قام علماء بازالة خلايا لها علاقة بالعمر (p16Ink4a-positive cells) من فئران فزاد مدى العمر لهم 25% وكانوا اكثر صحة 😍https://t.co/8HLKpN2u4K
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature : Nature Publishing Group https://t.co/9AVxMhMpv8
Senescent cells removed: larger and healthier life? https://t.co/bRDtOxbu97
A milestone towards immortality? Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature https://t.co/MdB5mbSplg
RT @RoosterBio: The fountain of youth: Remove senescent cells? #aging https://t.co/BKLYDH6T8O
RT @RoosterBio: The fountain of youth: Remove senescent cells? #aging https://t.co/BKLYDH6T8O
The fountain of youth: Remove senescent cells? #aging https://t.co/BKLYDH6T8O
遺伝子改変マウスの実験だが、老化した細胞を除く薬剤を投与すると寿命が100日以上延びた。心臓腎臓にも良い効果。 人で同様の薬剤が可能かどうか?既に探索は行われているそう 自然に生じるp16Ink4a陽性細胞は健康寿命を短くする https://t.co/Vh4z5VeQoF
RT @RegMedNet: Clearance of p16Ink4a+ (senescent) cells in mice extends healthy lifespan & delays tumorigenesis https://t.co/C4ai7jZ9TS @On…
Clearance of p16Ink4a+ (senescent) cells in mice extends healthy lifespan & delays tumorigenesis https://t.co/C4ai7jZ9TS @OncologyCentral
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/7ajVia8iea
RT @NatureKorea: 네이처 하이라이트:수명과 건강 상태에 영향을 주는 자연 발생적인 노화 세포 https://t.co/pZxd11vJzh
RT @RTB_HRoss: Removal of “senile” cells in mice delays aging and increases healthy lifespan. https://t.co/e2RU8KofgL
Awesome paper in JC today! Who wants to live forever? https://t.co/ARKTWj0O9b
RT @dd414a1d9b59447: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/xAmjtmauxz
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/xAmjtmauxz
네이처 하이라이트:수명과 건강 상태에 영향을 주는 자연 발생적인 노화 세포 https://t.co/pZxd11vJzh
《自然》要点:衰老细胞的有害影响 https://t.co/3uLMhWR3V2
RT @KeDaHuntr: A fascinating paper: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/1YcCZkOGVC
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/xq7lO0SC1h
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/lvETr4htjk
RT @RTB_HRoss: Removal of “senile” cells in mice delays aging and increases healthy lifespan. https://t.co/e2RU8KofgL
Removal of “senile” cells in mice delays aging and increases healthy lifespan. https://t.co/e2RU8KofgL
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/F3xs09CjH0
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/JB6baqVENF
Eliminating p16[Ink4a]-expressing senescent cells increased lifespan thru multiple systems. https://t.co/i7QS5cXoCd https://t.co/pEYTk2VYwJ
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/NrEYroTiA1
RT @IBellantuono: Senescence cells removal delays onset of multiple age-related diseases including cancer in mice https://t.co/sLFXncyJ4G -…
Naturally occurring p16Ink4a-positive #Cells shorten healthy lifespan https://t.co/wgbGfgWJiv #Health #Medicine https://t.co/2zWRN3751S
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature : Nature Publishing Group https://t.co/HXbYVe4hqh
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
Removal of accumulated senescent cells could extend healthy lifespan in humans @NatureNews via @NYTNow https://t.co/y9O4mIU6fz
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
RT @OrenoReSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/RYuXAtrObQ p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/a0UhroJXuq
RT @OrenoReSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/RYuXAtrObQ p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/a0UhroJXuq
RT @OrenoReSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/RYuXAtrObQ p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/a0UhroJXuq
RT @OrenoReSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/RYuXAtrObQ p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/a0UhroJXuq
老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/RYuXAtrObQ p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/a0UhroJXuq
RESEARCH: Extend Lifespan in Mice by as Much as 35 Percent #Antiaging https://t.co/lzc5CQQDIv https://t.co/bNCCVmUtt2
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
RT @OrenoSource: 老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
老化した細胞の除去で寿命が延長、マウス実験で確認 AFP https://t.co/JY9gT6Gk6a p16を発現した細胞が死ぬようにすると個体の寿命が延長した。(nature原著)→ https://t.co/3nc2JTFl3C
I like the science presented here but the abstract, press release and coverage are misleading (1/x) @edyong209 https://t.co/xz2RMh4159
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
Killing off inactive cells that carry a stress protein may help prolong health & life. https://t.co/DdJZ4iwnP5 This week's #mustread @Nature
Destroying worn-out cells makes mice live longer #nature #senescent #cells #targeting #agediseases https://t.co/MMaJr56lJA
https://t.co/atxIZhTtmJ Tempo de vida de ratos prolongado em 35%. Seres humanos serão os próximos? #nature #journalofscience #research
A fascinating paper: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/1YcCZkOGVC
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/Pz9LZUfC7l
NowBrowsing: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature : Nature Publishing Gro…: https://t.co/F2BkSWxa78
RT @nature: Removing so-called senescent cells from ‘middle-aged’ mice extends their lifespan and delays age-related decline https://t.co/x…
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan : Nature : Nature... https://t.co/oUHgd5yzwx
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @mjsteinbaugh: Naturally occurring p16Ink4a-positive cells shorten healthy lifespan https://t.co/mUxLuGJjaA
Mice live ~35% longer, no adverse effects. https://t.co/H5M5aDMU4Q
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…
RT @NatureBiotech: Killing off senescent cells in mice that age normally reduces signs of aging and extends lifespan. https://t.co/7rk73aaI…