Chapter title |
Anatomy and Physiology of Multiscale Modeling and Simulation in Systems Medicine.
|
---|---|
Chapter number | 17 |
Book title |
Systems Medicine
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3283-2_17 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3282-5, 978-1-4939-3283-2
|
Authors |
Mizeranschi, Alexandru, Groen, Derek, Borgdorff, Joris, Hoekstra, Alfons G, Chopard, Bastien, Dubitzky, Werner, Alexandru Mizeranschi, Derek Groen, Joris Borgdorff, Alfons G. Hoekstra, Bastien Chopard, Werner Dubitzky, Hoekstra, Alfons G. |
Editors |
Ulf Schmitz, Olaf Wolkenhauer |
Abstract |
Systems medicine is the application of systems biology concepts, methods, and tools to medical research and practice. It aims to integrate data and knowledge from different disciplines into biomedical models and simulations for the understanding, prevention, cure, and management of complex diseases. Complex diseases arise from the interactions among disease-influencing factors across multiple levels of biological organization from the environment to molecules. To tackle the enormous challenges posed by complex diseases, we need a modeling and simulation framework capable of capturing and integrating information originating from multiple spatiotemporal and organizational scales. Multiscale modeling and simulation in systems medicine is an emerging methodology and discipline that has already demonstrated its potential in becoming this framework. The aim of this chapter is to present some of the main concepts, requirements, and challenges of multiscale modeling and simulation in systems medicine. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 13 | 100% |
Demographic breakdown
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Student > Bachelor | 3 | 23% |
Researcher | 2 | 15% |
Other | 1 | 8% |
Student > Ph. D. Student | 1 | 8% |
Student > Doctoral Student | 1 | 8% |
Other | 2 | 15% |
Unknown | 3 | 23% |
Readers by discipline | Count | As % |
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Computer Science | 3 | 23% |
Medicine and Dentistry | 2 | 15% |
Agricultural and Biological Sciences | 1 | 8% |
Chemical Engineering | 1 | 8% |
Chemistry | 1 | 8% |
Other | 1 | 8% |
Unknown | 4 | 31% |