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Poly(ADP-ribose) Polymerase

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Cover of 'Poly(ADP-ribose) Polymerase'

Table of Contents

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    Book Overview
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    Chapter 1 Approaches to Detect PARP-1 Activation In Vivo, In Situ, and In Vitro
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    Chapter 2 Quantification of Poly(ADP-Ribose) In Vitro: Determination of the ADP-Ribose Chain Length and Branching Pattern
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    Chapter 3 Assay for Protein Modification by Poly-ADP-Ribose In Vitro
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    Chapter 4 Identification of Distinct Amino Acids as ADP-Ribose Acceptor Sites by Mass Spectrometry
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    Chapter 5 Noncovalent Protein Interaction with Poly(ADP-Ribose)
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    Chapter 6 Noncovalent pADPr Interaction with Proteins and Competition with RNA for Binding to Proteins
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    Chapter 7 Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins.
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    Chapter 8 Detecting and Quantifying pADPr In Vivo
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    Chapter 9 Purification of Recombinant Poly(ADP-Ribose) Polymerases
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    Chapter 10 Methods for purification of proteins associated with cellular poly(ADP-ribose) and PARP-specific poly(ADP-ribose).
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    Chapter 11 Purification and Characterization of Poly(ADP-Ribosyl)ated DNA Replication/Repair Complexes
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    Chapter 12 PARP1 Genomics: Chromatin Immunoprecipitation Approach Using Anti-PARP1 Antibody (ChIP and ChIP-seq)
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    Chapter 13 Purification of Human PARP-1 and PARP-1 Domains from Escherichia coli for Structural and Biochemical Analysis
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    Chapter 14 Regulation of Chromatin Structure by PARP-1
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    Chapter 15 The Use of PARP Inhibitors in Cancer Therapy: Use as Adjuvant with Chemotherapy or Radiotherapy; Use as a Single Agent in Susceptible Patients; Techniques Used to Identify Susceptible Patients
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    Chapter 16 Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies
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    Chapter 17 Assays for hypermethylation of the BRCA1 gene promoter in tumor cells to predict sensitivity to PARP-inhibitor therapy.
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    Chapter 18 Generation of Poly(ADP-ribosyl)ation Deficient Mutants of the Transcription Factor, CTCF.
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    Chapter 19 Phenotypic Characterization of Parp-1 and Parp-2 Deficient Mice and Cells
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    Chapter 20 Poly(ADP-ribosyl)ation Pathways in Mammals: The Advantage of Murine PARG Null Mutation
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    Chapter 21 Genetic Approaches to Targeting Multiple PARP Genes in a Mammalian Genome
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    Chapter 22 Approaches to Separate and Identify PolyADP-Ribosylated Proteins Using Poly(ADP-Ribose) Glycohydrolase-Knockout Drosophila
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    Chapter 23 Immunolocalization of Poly ADP-Ribose on Drosophila Polytene Chromosomes
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    Chapter 24 The Immunodetection of pADPr in Drosophila Tissues: Immunostaining of Thick Sections; Immuno-EM
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    Chapter 25 Poly(ADP-Ribose) Metabolism Analysis in the Nematode Caenorhabditis elegans
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    Chapter 26 Genetic Dissection of PARylation in the Filamentous Fungus Neurospora crassa
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    Chapter 27 Purification of the Poly-ADP-Ribose Polymerase-Like Thermozyme from the Archaeon Sulfolobus solfataricus
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    Chapter 28 Strategies Employed for the Development of PARP Inhibitors
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    Chapter 29 Small-Molecule Collection and High-Throughput Colorimetric Assay to Identify PARP1 Inhibitors
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    Chapter 30 Purification of the Poly-ADP-Ribose Polymerase-Like Thermozyme from the Archaeon Sulfolobus solfataricus
Attention for Chapter 26: Genetic Dissection of PARylation in the Filamentous Fungus Neurospora crassa
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Chapter title
Genetic Dissection of PARylation in the Filamentous Fungus Neurospora crassa
Chapter number 26
Book title
Poly(ADP-ribose) Polymerase
Published by
Humana Press, Totowa, NJ, January 2011
DOI 10.1007/978-1-61779-270-0_26
Pubmed ID
21870276
Book ISBNs
978-1-61779-269-4, 978-1-61779-270-0
Authors

Gregory O. Kothe, Kothe, Gregory O.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 43%
Unspecified 1 14%
Lecturer > Senior Lecturer 1 14%
Unknown 2 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 29%
Biochemistry, Genetics and Molecular Biology 2 29%
Unspecified 1 14%
Unknown 2 29%

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