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Non-coding RNA and the Reproductive System

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Attention for Chapter 8: Non-coding RNAs in Prostate Cancer: From Discovery to Clinical Applications.
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Chapter title
Non-coding RNAs in Prostate Cancer: From Discovery to Clinical Applications.
Chapter number 8
Book title
Non-coding RNA and the Reproductive System
Published in
Advances in experimental medicine and biology, December 2015
DOI 10.1007/978-94-017-7417-8_8
Pubmed ID
Book ISBNs
978-9-40-177415-4, 978-9-40-177417-8
Authors

Ceder, Yvonne, Yvonne Ceder

Editors

Dagmar Wilhelm, Pascal Bernard

Abstract

Prostate cancer is a heterogeneous disease for which the molecular mechanisms are still not fully elucidated. Prostate cancer research has traditionally focused on genomic and epigenetic alterations affecting the proteome, but over the last decade non-coding RNAs, especially microRNAs, have been recognized to play a key role in prostate cancer progression. A considerable number of individual microRNAs have been found to be deregulated in prostate cancer and their biological significance elucidated in functional studies. This review will delineate the current advances regarding the involvement of microRNAs and their targets in prostate cancer biology as well as their potential usage in the clinical management of the disease. The main focus will be on microRNAs contributing to initiation and progression of prostate cancer, including androgen signalling, cellular plasticity, stem cells biology and metastatic processes. To conclude, implications on potential future microRNA-based therapeutics based on the recent advances regarding the interplay between microRNAs and their targets are discussed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 19%
Student > Ph. D. Student 4 19%
Student > Doctoral Student 3 14%
Researcher 3 14%
Student > Master 2 10%
Other 2 10%
Unknown 3 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 29%
Medicine and Dentistry 4 19%
Agricultural and Biological Sciences 3 14%
Computer Science 1 5%
Mathematics 1 5%
Other 2 10%
Unknown 4 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2015.
All research outputs
#20,298,249
of 22,835,198 outputs
Outputs from Advances in experimental medicine and biology
#3,969
of 4,951 outputs
Outputs of similar age
#326,317
of 388,813 outputs
Outputs of similar age from Advances in experimental medicine and biology
#303
of 403 outputs
Altmetric has tracked 22,835,198 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,951 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 388,813 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 403 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.