| Chapter title |
ICOS Expression as Immunologic Marker in Immune Activating Monoclonal Antibodies.
|
|---|---|
| Chapter number | 13 |
| Book title |
Tumor Immunology
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3338-9_13 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3336-5, 978-1-4939-3338-9
|
| Authors |
Riccardo Danielli M.D., Ornella Cutaia Ph.D., Carolina Fazio Ph.D., Erika Bertocci Ph.D., Ester Fonsatti Ph.D., Michele Maio M.D., Luana Calabrò M.D., Riccardo Danielli, Ornella Cutaia, Carolina Fazio, Erika Bertocci, Ester Fonsatti, Michele Maio, Luana Calabrò, Danielli, Riccardo, Cutaia, Ornella, Fazio, Carolina, Bertocci, Erika, Fonsatti, Ester, Maio, Michele, Calabrò, Luana |
| Editors |
Attilio Bondanza, Monica Casucci |
| Abstract |
Compelling experimental evidences point to monitoring of the absolute number of circulating ICOS-positive T cells as an early predictive marker of clinical activity of anti-CTLA-4 antibodies in cancer patients. Here, we report available data focusing on this issue and operative procedures to detect ICOS expression on circulating peripheral blood mononuclear cells during CTLA-4 blockade therapy. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 3 | 30% |
| Researcher | 2 | 20% |
| Student > Bachelor | 1 | 10% |
| Other | 1 | 10% |
| Student > Ph. D. Student | 1 | 10% |
| Other | 1 | 10% |
| Unknown | 1 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 30% |
| Immunology and Microbiology | 3 | 30% |
| Agricultural and Biological Sciences | 2 | 20% |
| Nursing and Health Professions | 1 | 10% |
| Unknown | 1 | 10% |