Chapter title |
Development of Fasciola Vaccine in an Animal Model.
|
---|---|
Chapter number | 8 |
Book title |
Vaccine Design
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3389-1_8 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3388-4, 978-1-4939-3389-1
|
Authors |
Krai Meemon Ph.D., Prasert Sobhon, Krai Meemon |
Editors |
Sunil Thomas |
Abstract |
Fasciola hepatica and F. gigantica are the parasites that cause the zoonotic parasitic disease called fasciolosis. Although several anthelmintic drugs have been used to treat these parasitic infections, recombinant protein vaccines have been developed to overcome the anthelmintic resistance that has recently been reported in many regions of the world. These vaccines have been shown to induce high levels of immune responses and high percentages of protection in experimental and large animals. Efficacies of these vaccines suggest they could be an alternative and sustainable strategy to prevent fasciolosis in animals as well as humans in the future. The purpose of this chapter is to provide a protocol to develop a recombinant protein-based vaccine against Fasciola infection in mice. Moreover, this method can also be used as a guideline when the vaccination is performed in larger animals. |
Mendeley readers
Geographical breakdown
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Uruguay | 1 | 6% |
Egypt | 1 | 6% |
Unknown | 16 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 17% |
Student > Bachelor | 2 | 11% |
Professor > Associate Professor | 2 | 11% |
Student > Master | 2 | 11% |
Professor | 1 | 6% |
Other | 3 | 17% |
Unknown | 5 | 28% |
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Agricultural and Biological Sciences | 1 | 6% |
Other | 3 | 17% |
Unknown | 6 | 33% |